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A Study Using Intravitreal Injections of a Small Interfering RNA in Patients With Age-Related Macular Degeneration

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Study of TD101, a Small Interfering RNA (siRNA) Designed for Treatment of Pachyonychia Congenita

• Authors : Sancy Leachman/Principal Investigator

• Source: A Single-Center, Placebo-Controlled, Rising Dose to Tolerance and Safety Study of TD101, an siRNA Designed for Treatment of Pachyonychia Congenita

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Safety and Efficacy Study of Small Interfering RNA Molecule (Cand5) to Treat Diabetic Macular Edema

• Authors : Denis O'Shaughnessy

• Source: A Phase II, Pharmacokinetic, Randomized, Double-Masked, Controlled, Dose Comparison Study of Cand5 for Intravitreal Injection for the Treatment of Diabetic Macular Edema

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The First-in-human Study of SRN-001 in Healthy Participants

• Source: Yoon PO, Park JW, Lee CM, Kim SH, Kim HN, Ko Y, Bae SJ, Yun S, Park JH, Kwon T, Kim WS, Lee J, Lu Q, Kang HR, Cho WK, Elias JA, Yang JS, Park HO, Lee K, Lee CG. Self-assembled Micelle

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CD4+ T Cells and S100A7 Epression in Normal and Psoriatic Skin: A Histological and Histochemical Study

• Authors : Ashrakat Abdelhamid Amin, demonastrator at department of histology and cell biology ,Sohag university

• Source: Iskandar IYK, Parisi R, Griffiths CEM, Ashcroft DM; Global Psoriasis Atlas. Systematic review examining changes over time and variation in the incidence and prevalence of psoriasis by age and gender.

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Genomic Responses of Human Immune and Non-Immune Cells to Glucocorticoids

• Source: Khoury P, Stokes K, Gadkari M, Makiya MA, Legrand F, Hu Z, Klion A, Franco LM. Glucocorticoid-induced eosinopenia in humans can be linked to early transcriptional events. Allergy. 2018

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A Phase 3 Study of VSA001 in Chinese Adults With Familial Chylomicronemia Syndrome

• Source: Phase 3 Study to Evaluate the Efficacy and Safety of ARO-APOC3 in Chinese Adults With Familial Chylomicronemia Syndrome

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Analysis of the Mechanisms of Actions of Heat Shock Protein (Hsp27) Responsible of the Androgen-independent Evolution in Prostate Cancer

• Source: Analysis of the Mechanisms of Actions of Hsp27 Responsible of the Androgen-independent Evolution in Prostate Cancer

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AR-inhibitor Bicalutamide in Treating Patients With TNBC (Arbre)

• Authors : Wenzhou Medical University; The First People's Hospital of Lianyungang; Wuxi People's Hospital ...

• Source: Hu R, Dawood S, Holmes MD, Collins LC, Schnitt SJ, Cole K, Marotti JD, Hankinson SE, Colditz GA, Tamimi RM. Androgen receptor expression and breast cancer survival in postmenopausal women. Clin Cancer

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I5NP for Prophylaxis of Delayed Graft Function in Kidney Transplantation

• Source: Controlled, Randomized, Prospective, Double-Blind, Multicenter, Phase I/II, Dose-Escalation Study of the Safety, PK, and Clinical Activity of I5NP for Prophylaxis of Delayed Graft Function in Patients

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