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Role of Urinary Sphingosine 1-Phosphate as a Biomarker for Detrusor Hyperactivity in Multiple Sclerosis (SEP-1)

• Source: Prospective Study Evaluating the Role of Urinary Sphingosine 1-Phosphate as a Biomarker for Detrusor Hyperactivity in Multiple Sclerosis

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Opaganib, a Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia

• Source: Opaganib, a Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia: a Randomized, Double-blind, Placebo-Controlled Phase 2/3 Study, in Adult Subjects Hospitalized

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Phase 2 Study of Fingolimod in Lung Cancers

• Authors : Mariam Alexander, Assistant Professor-Faculty

• Source: A Phase II Study of Fingolimod in Patients With Non-Small Cell and Small Cell Lung Cancer

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Evaluating the Association Between Sphingolipid Metabolites and Post-hepatectomy Liver Failure

• Source: Evaluating the Association Between Sphingolipid Metabolites and Post-hepatectomy Liver FailureRahbari NN, Garden OJ, Padbury R, Brooke-Smith M, Crawford M, Adam R, Koch M, Makuuchi M, Dematteo

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Identification of Biomarkers and Molecular Targets Involved on Intervertebral Disc Degeneration and Discogenic Pain

• Source: Development of New Diagnostic, Prognostic and Therapeutic Strategies in the Field of Degenerative Disc Disease: Identification of Biomarkers and Molecular Targets Involved in Discogenic Pain and

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Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness

• Source: Strategies for the Development of Multimodal Therapies in Tumors of the Central Nervous System: Identification of New Molecular and Metabolic Targets Implicated in Survival and Chemoresistance

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The Role of Pioglitazone in Vascular Transcriptional Remodeling (PREVALENT)

• Authors : Andrei Carvalho Sposito, Professor of cardiology

• Source: The Role of Pioglitazone in Vascular Transcriptional Remodeling in Individuals Undergoing Coronary Artery Bypass Grafting

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SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International) (SPLIS-OSPRI)

• Source: Sphingosine Phosphate Lyase Insufficiency Syndrome - Observational Study and Patient Registry (International)Lovric S, Goncalves S, Gee HY, Oskouian B, Srinivas H,

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Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation

• Authors : Ahmed Osama Gaber, MD, Chair, Department of Surgery

• Source: A Phase 2, Randomized, Placebo-Controlled Study to Evaluate Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney TransplantationGilenya [package insert].

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Effects of Ozanimod on Immune-mediated Mechanisms of Neurodegeneration in Multiple Sclerosis - a Preclinical Study

• Authors : University of Rome Tor Vergata; Fabio Buttari, Principal Investigator

• Source: Effects of Ozanimod on Immune-mediated Mechanisms of Neurodegeneration in Multiple Sclerosis - a Preclinical StudyMusella A, Gentile A, Guadalupi L, Rizzo FR, De Vito F, Fresegna D, Bruno A,

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