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Report

Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Docetaxel and Prednisone (CRPC)

  • Source: A Phase 1b/2 Study of Docetaxel and Prednisone, With or Without ISIS 183750 (an eIF4E Inhibitor), in Patients With Castrate-Resistant Prostate Cancer

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Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Carboplatin and Paclitaxel (NSCLC)

  • Source: A Phase 1b/2 Study of Carboplatin-Paclitaxel, With or Without ISIS 183750 (an eIF4E Inhibitor), in Patients With Stage IV Non-Small Cell Lung Cancer

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The Involvement of Eukaryotic Translation Initiation Factor 4E (eIF4E) in Human Placental Implantation and in the Pathological Pregnancies: Preeclampsia and IUGR

  • Source: The Involvement of Eukaryotic Translation Initiation Factor 4E (eIF4E) in Human Placental Implantation and in the Pathological Pregnancies: Preeclampsia and IUGR.

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A Study of Ribavirin to Treat M4 and M5 Acute Myelocytic Leukemia (Borden-001)

  • Source: A Phase II Study of Ribavirin in Refractory of Relapsed Acute Myelocytic Leukemia M4 and M5 SubtypesTopisirovic I, Guzman ML, McConnell MJ, Licht JD, Culjkovic B, Neering SJ, Jordan CT, Borden

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Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients (AML)

  • Authors : Jane Liesveld, Principal INvestigator

  • Source: A Phase I/II Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML PatientsLiesveld JL, Baran A, Azadniv M, Misch H, Nedrow K, Becker M, Loh KP, O'Dwyer KM,

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Use of Ribavirin and Low Dose Ara-C to Treat Acute Myeloid Leukemia

  • Source: A Phase I/II Study of Ribavirin and Low-dose Cytarabine Arabinoside (Ara-C) in Acute Myeloid Leukemia (AML) M4 and M5 Subtypes, and AML With High eIF4E Expression

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ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer

  • Authors : Tim Greten, M.D., Principal Investigator

  • Source: A Phase I/II Study of ISIS 183750 in Combination With Irinotecan in Irinotecan-refractory Colorectal CancerDuffy AG, Makarova-Rusher OV, Ulahannan SV, Rahma OE, Fioravanti S, Walker M, Abdullah

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Treatment With Ribavirin for Patients With Metastatic Breast Cancer

  • Authors : Wilson Miller, Principal Investigator

  • Source: A Phase I/II Exploratory Study of Ribavirin in Metastatic Breast Cancer Expressing Elevated eIF4EKentsis A, Topisirovic I, Culjkovic B, Shao L, Borden KL.

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Involvement of the Translation Initiation Factors in Resolution of Inflammation in the Elderly Population

  • Source: The Involvement of the Translation Initiation Factors eIF4E and eIF4G in Resolution of Inflammation in the Elderly Population

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