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Assessment of the Impact of Increased Production of Reactive Oxygen Species Produced During Repeated Sessions of Hyperbaric Oxygen Therapy in Patients Undergoing Radiotherapy for Neoplasia, on the Occurrence of DNA Damage (OXYBAR)

• Source: Assessment of the Impact of Increased Production of Reactive Oxygen Species Produced During Repeated Sessions of Hyperbaric Oxygen Therapy in Patients Undergoing Radiotherapy for Neoplasia, on the

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Evaluating the Efficacy and Safety of Fulvestrant Plus DNA Damage Repair Inhibitors After a CDK4/6 Inhibitor (Post-CDK)

• Authors : Seock-Ah Im, Professor

• Source: A Phase II Open Label, Umbrella Study Evaluating the Efficacy and Safety of Fulvestrant Plus DNA Damage Repair Inhibitors in Hormone

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Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

• Source: Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA DamageBond GL, Hu W, Bond EE, Robins H, Lutzker

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The Effect of Cardiac Rehabilitation on Oxidative DNA Damage and Inflammation in Patients With Coronary Artery Disease

• Authors : Hasan Kara, Professor Assistant Medical Doctor

• Source: The Effect of Cardiac Rehabilitation on Oxidative DNA Damage and Inflammation in Patients With Coronary Artery Disease

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RP-3500 and Olaparib in DNA Damage Repair Pathway Deficient Relapsed/Refractory Chronic Lymphocytic Leukemia (CORONADO CLL)

• Authors : Repare Therapeutics

• Source: A Phase Ib/II Trial of Combination RP-3500 and Olaparib in DNA Damage Repair Pathway Deficient Relapsed/Refractory Chronic Lymphocytic

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Study of Tuvusertib (M1774) in Combination With DNA Damage Response Inhibitor or Immune Checkpoint Inhibitor (DDRiver Solid Tumors 320)

• Authors : Merck KGaA, Darmstadt, Germany

• Source: An Open-label, Multicenter Phase Ib Study of the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of the ATR Inhibitor Tuvusertib (M1774) in Combination With

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Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes (OPTION-DDR)

• Authors : Canadian Institutes of Health Research (CIHR)

• Source: A Randomized Phase III Trial Investigating Platinum and Taxane Chemotherapy in Metastatic Castration Resistant Prostate Cancer Patients With Alterations in DNA

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Molecular Imaging of DNA Damage Response by [18F]-Olaparib PET (18F]-olaparib)

• Source: Molecular Imaging of DNA Damage Response by [18F]-Olaparib PET

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Temporal Immunologic Changes With Hypofractionated Radiation-Induced DNA Damage in Breast Cancer

• Authors : Artidis

• Source: Quantifying Temporal Immunologic Changes With Hypofractionated Radiation-Induced DNA Damage in Breast Cancer

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Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects

• Authors : National Cancer Institute (NCI); Janssen, LP; Marc Dall'Era, MD, Principal Investigator

• Source: Phase II Trial of PARP Inhibitor Niraparib for Men With High Risk Prostate Cancer and DNA Damage Response Defects

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