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Academic Journal

Using mice from different breeding sites fails to improve replicability of results from single-laboratory studies

Subjects: Institute of Anatomy; Neuroscience Center Zurich; Institute of Veterinary Pharmacology and Toxicology

  • Source: Jaric, Ivana; Voelkl, Bernhard; Amrein, Irmgard; Wolfer, David P; Novak, Janja; Detotto, Carlotta; Weber-Stadlbauer, Ulrike; Meyer, Urs; Manuella, Francesca; Mansuy, Isabelle M; Würbel, Hanno (2024).

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Academic Journal

Sex-divergent effects of hindbrain GLP-1-producing neuron activation in rats

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Lopez-Ferreras, Lorena; Asker, Mohammed; Krieger, Jean-Philippe; Skibicka, Karolina Patrycja (2023). Sex-divergent effects of hindbrain GLP-1-producing neuron activation in rats. Frontiers in

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Academic Journal

A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Long, Fen; Bhatti, Memoona R; Kellenberger, Alexandra; Sun, Wenfei; Modica, Salvatore; Höring, Marcus; Liebisch, Gerhard; Krieger, Jean-Philippe; Wolfrum, Christian; Challa, Tenagne D (2023). A

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Academic Journal

Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Asker, Mohammed; Krieger, Jean‐Philippe; Liles, Amber; Tinsley, Ian C; Borner, Tito; Maric, Ivana; Doebley, Sarah; Furst, C Daniel; Börchers, Stina; Longo, Francesco; Bhat, Yashaswini R; De Jonghe,

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Academic Journal

An appetite for aggressive behavior? Female rats, too, derive reward from winning aggressive interactions

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Börchers, Stina; Carl, Jil; Schormair, Katharina; Krieger, Jean-Philippe; Asker, Mohammed; Edvardsson, Christian E; Jerlhag, Elisabeth; Skibicka, Karolina P (2023). An appetite for aggressive

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Academic Journal

Somatostatin Containing δ-Cell Number Is Reduced in Type-2 Diabetes

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Kothegala, Lakshmi; Miranda, Caroline; Singh, Meetu; Krieger, Jean-Philippe; Gandasi, Nikhil R (2023). Somatostatin Containing δ-Cell Number Is Reduced in Type-2 Diabetes. International Journal of

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Academic Journal

Susceptibility and resilience to maternal immune activation are associated with differential expression of endogenous retroviral elements

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Herrero, Felisa; Mueller, Flavia S; Gruchot, Joel; Küry, Patrick; Weber-Stadlbauer, Ulrike; Meyer, Urs (2023). Susceptibility and resilience to maternal immune activation are associated with

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Academic Journal

Interplay between activation of endogenous retroviruses and inflammation as common pathogenic mechanism in neurological and psychiatric disorders

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Gruchot, Joel; Herrero, Felisa; Weber-Stadlbauer, Ulrike; Meyer, Urs; Küry, Patrick (2023). Interplay between activation of endogenous retroviruses and inflammation as common pathogenic mechanism in

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Academic Journal

Prefrontal microglia deficiency during adolescence disrupts adult cognitive functions and synaptic structure: A follow-up study in female mice

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: von Arx, Anina S; Dawson, Kara; Lin, Han-Yu; Mattei, Daniele; Notter, Tina; Meyer, Urs; Schalbetter, Sina M (2023). Prefrontal microglia deficiency during adolescence disrupts adult cognitive

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Academic Journal

Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Gruchot, Joel; Lewen, Isabel; Dietrich, Michael; Reiche, Laura; Sindi, Mustafa; Hecker, Christina; Herrero, Felisa; Charvet, Benjamin; Weber-Stadlbauer, Ulrike; Hartung, Hans-Peter; Albrecht, Philipp;

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Academic Journal

P38 Mediates Tumor Suppression through Reduced Autophagy and Actin Cytoskeleton Changes in NRAS-Mutant Melanoma

Subjects: Functional Genomics Center Zurich; Institute of Veterinary Pharmacology and Toxicology; Dermatology Clinic

  • Source: Banik, Ishani; Ghosh, Adhideb; Beebe, Erin; Burja, Blaž; Bertoncelj, Mojca Frank; Dooley, Christopher M; Markkanen, Enni; Dummer, Reinhard; Busch-Nentwich, Elisabeth M; Levesque, Mitchell P (2023).

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Academic Journal

Assessment of genetically modified maize MON 87419 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2017‐140)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Animal dietary exposure in the risk assessment of feed derived from genetically modified plants

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Risk assessment of additional information on maize MIR162

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified oilseed rape MS8, RF3 and MS8 × RF3 for renewal authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐024)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified maize GA21 × T25 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐DE‐2016‐137)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified cotton COT102 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐DE‐2017‐141)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Naegeli, Hanspeter; Moreno, Francisco Javier;

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Academic Journal

ASH1L-MRG15 methyltransferase deposits H3K4me3 and FACT for damage verification in nucleotide excision repair

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Maritz, Corina; Khaleghi, Reihaneh; Yancoskie, Michelle N; Diethelm, Sarah; Brülisauer, Sonja; Ferreira, Natalia Santos; Jiang, Yang; Sturla, Shana J; Naegeli, Hanspeter (2023). ASH1L-MRG15

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Academic Journal

Guidance on protocol development for EFSA generic scientific assessments

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: More, Simon; Bampidis, Vasileios; Benford, Diane; Bragard, Claude; Hernández‐Jerez, Antonio; Bennekou, Susanne Hougaard; Koutsoumanis, Konstantinos Panagiotis; Lambré, Claude; Machera, Kyriaki;

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Academic Journal

Deciphering Stromal Changes between Metastatic and Non-metastatic Canine Mammary Carcinomas

Subjects: Functional Genomics Center Zurich; Institute of Veterinary Pharmacology and Toxicology; Institute of Veterinary Pathology

  • Source: Ettlin, Julia; Bauer, Alina; Opitz, Lennart; Malbon, Alexandra; Markkanen, Enni (2023). Deciphering Stromal Changes between Metastatic and Non-metastatic Canine Mammary Carcinomas. Journal of Mammary

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Academic Journal

To incise or not and where: SET-domain methyltransferases know

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Yancoskie, Michelle N; Maritz, Corina; van Eijk, Patrick; Reed, Simon H; Naegeli, Hanspeter (2023). To incise or not and where: SET-domain methyltransferases know. Trends in Biochemical Sciences,

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Academic Journal

Proteomic profiling of canine fibrosarcoma and adjacent peritumoral tissue

Subjects: Functional Genomics Center Zurich; Institute of Veterinary Pharmacology and Toxicology; Institute of Veterinary Pathology

  • Source: Beebe, Erin; Pöschel, Amiskwia; Kunz, Laura; Wolski, Witold; Motamed, Zahra; Meier, Daniela; Guscetti, Franco; Nolff, Mirja C; Markkanen, Enni (2023). Proteomic profiling of canine fibrosarcoma and

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Academic Journal

Interaction of the pre- and postnatal environment in the maternal immune activation model

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Gundacker, Anna; Cuenca Rico, Laura; Stoehrmann, Peter; Tillmann, Katharina E; Weber-Stadlbauer, Ulrike; Pollak, Daniela D (2023). Interaction of the pre- and postnatal environment in the maternal

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Book

Sources and Translational Relevance of Heterogeneity in Maternal Immune Activation Models

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Meyer, Urs (2022). Sources and Translational Relevance of Heterogeneity in Maternal Immune Activation Models. In: Meyer, Urs. Current Topics in Behavioral Neurosciences. Zuerich: Springer, 1-21.

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Academic Journal

Scientific Opinion on development needs for the allergenicity and protein safety assessment of food and feed products derived from biotechnology

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; George Firbank, Leslie; Guerche, Philippe; Hejatko, Jan; Naegeli, Hanspeter; Nogué, Fabien; Rostoks,

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Academic Journal

Assessment of new sequencing information for genetically modified cotton DAS‐24236‐5 × DAS‐21Ø23‐5

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Naegeli, Hanspeter; Moreno, Francisco Javier;

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Academic Journal

Assessment of genetically modified soybean A5547‐127 for renewal authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐020)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

'Nano-ghosts': Risk assessment of submicron-sized particles in food biased towards fictional 'nano'

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Naegeli, Hanspeter; Gsell, Corina (2022). "Nano-ghosts": Risk assessment of submicron-sized particles in food biased towards fictional "nano". EXCLI Journal, 21:279-299.

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Academic Journal

Assessment of genetically modified oilseed rape MON 94100 for food and feed uses, under regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2020‐169)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Evaluation of existing guidelines for their adequacy for the food and feed risk assessment of genetically modified plants obtained through synthetic biology

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Nogue, Fabien;

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Academic Journal

Assessment of genetically modified oilseed rape GT73 for renewal authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐026/1)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Risk assessment of a new bioinformatics evaluation of the insertion sites of genetically modified soybean event 40‐3‐2

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Updated scientific opinion on plants developed through cisgenesis and intragenesis

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified oilseed rape GT73 for placing on the market of isolated seed protein for food under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐026/2)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Criteria for risk assessment of plants produced by targeted mutagenesis, cisgenesis and intragenesis

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified cotton 281‐24‐236 × 3006‐210‐23 for renewal authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐019)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified maize MON 95379 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2020‐170)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified soybean MON 87701 × MON 89788 for renewal authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐022)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified Maize MON 87429 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2019‐161)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified soybean 40‐3‐2 for renewal authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐023)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Assessment of genetically modified soybean MON 87701 for renewal authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐021)

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mullins, Ewen; Bresson, Jean‐Louis; Dalmay, Tamas; Dewhurst, Ian Crawford; Epstein, Michelle M; Firbank, Leslie George; Guerche, Philippe; Hejatko, Jan; Moreno, Francisco Javier; Naegeli, Hanspeter;

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Academic Journal

Deficient DNA base-excision repair in the forebrain leads to a sex-specific anxiety-like phenotype in mice

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Mueller, Flavia S; Amport, René; Notter, Tina; Schalbetter, Sina M; Lin, Han-Yu; Garajova, Zuzana; Amini, Parisa; Weber-Stadlbauer, Ulrike; Markkanen, Enni (2022). Deficient DNA base-excision repair

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Academic Journal

Editorial: Looking at the Complete Picture: Tackling Broader Factors Important for Advancing the Validity of Preclinical Models in Disease

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Karl, Tim; Nithianantharajah, Jess; Weber-Stadlbauer, Ulrike (2022). Editorial: Looking at the Complete Picture: Tackling Broader Factors Important for Advancing the Validity of Preclinical Models in

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Academic Journal

Analyses of circRNA Expression throughout the Light-Dark Cycle Reveal a Strong Regulation of Cdr1as, Associated with Light Entrainment in the SCN

Subjects: Institute of Veterinary Pharmacology and Toxicology; 570 Life sciences; biology

  • Source: Ivanov, Andranik; Mattei, Daniele; Radscheit, Kathrin; Compagnion, Anne-Claire; Pett, Jan Patrick; Herzel, Hanspeter; Paolicelli, Rosa Chiara; Piwecka, Monika; Meyer, Urs; Beule, Dieter (2022).

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Academic Journal

Ergebnisse einer Umfrage zur ­Verschreibung von Antibiotika in der ­Veterinärmedizin

Subjects: Institute of Veterinary Pharmacology and Toxicology; Chair in Veterinary Epidemiology; 570 Life sciences

  • Source: Peter, R; Müntener, C R; Heim, D; Hartnack, Sonja; Naegeli, H (2022). Ergebnisse einer Umfrage zur ­Verschreibung von Antibiotika in der ­Veterinärmedizin. Schweizer Archiv für Tierheilkunde,

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