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Academic Journal

Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer's disease and type two diabetes

Subjects: Matrix metalloproteinases; Type 2 diabetes; Alzheimer Disease - metabolism

  • Source: Vargas-Soria , M , Ramos-Rodriguez , J J , Del Marco , A , Hierro-Bujalance , C , Carranza-Naval , M J , Calvo-Rodriguez , M , Veluw , S J V , Stitt , A W , Simó , R , Bacskai , B J , Infante-Garcia

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Academic Journal

A Human and Rhesus Macaque Interferon-Stimulated Gene Screen Shows That Over-Expression of ARHGEF3/XPLN Inhibits Replication of Hepatitis C Virus and Other Flavivirids

Subjects: interferon; ISG; Flaviviridae

  • Source: Bamford , C G G , Aranday-Cortes , E , Sanchez-Velazquez , R , Mullan , C , Kohl , A , Patel , A H , Wilson , S J & McLauchlan , J 2022 , ' A Human and Rhesus Macaque Interferon-Stimulated Gene Screen

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Academic Journal

Arsenic exposure and respiratory outcomes during childhood in the INMA study

Subjects: Arsenic - analysis - toxicity; Biomarkers; Asthma - chemically induced - epidemiology

  • Source: Signes-Pastor , A J , Díaz-Coto , S , Martinez-Camblor , P , Carey , M , Soler-Blasco , R , García-Villarino , M , Fernández-Somoano , A , Julvez , J , Carrasco , P , Lertxundi , A , Santa Marina ,

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Academic Journal

Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin

Subjects: Animals; Dihydrotestosterone/metabolism; Humans

  • Source: Frøbert , A M , Brohus , M , Toews , J N C , Round , P , Fröbert , O , Hammond , G L & Overgaard , M T 2022 , ' Characterization and comparison of recombinant full-length ursine and human sex

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Academic Journal

Hay vs. haylage; forage type influences the equine urinary metabonome and faecal microbiota

Subjects: forage; hay; haylage

  • Source: Leng , J , McNally , S , Walton , G , Swann , J , Proudman , C , Argo , C , Emery , S , La Ragione , R & Eustace , R 2022 , ' Hay vs. haylage; forage type influences the equine urinary metabonome and

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Academic Journal

The antibiotic doxycycline impairs cardiac mitochondrial and contractile function

Subjects: Aging/metabolism; Animals; Anti-Bacterial Agents/pharmacology

  • Source: Wüst , R C I , Coolen , B F , Held , N M , Daal , M R R , Tazehkandi , V A , Baks‐Te Bulte , L , Wiersma , M , Kuster , D W D , Brundel , B J J M , van Weeghel , M , Strijkers , G J & Houtkooper ,

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Academic Journal

Quantification of mouse heart left ventricular function, myocardial strain, and hemodynamic forces by cardiovascular magnetic resonance imaging

Subjects: Animals; Heart Ventricles/diagnostic imaging; Hemodynamics

  • Source: Daal , M R R , Strijkers , G J , Calcagno , C , Garipov , R R , Wüst , R C I , Hautemann , D & Coolen , B F 2021 , ' Quantification of mouse heart left ventricular function, myocardial strain, and

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Academic Journal

The combination of smoking with vitamin D deficiency impairs skeletal muscle fiber hypertrophy in response to overload in mice

Subjects: Animals; Humans; Hypertrophy

  • Source: Ajime , T T , Serre , J , Wust , R C I , Burniston , J G , Maes , K , Janssens , W , Troosters , T , Gayan-Ramirez , G & Degens , H 2021 , ' The combination of smoking with vitamin D deficiency

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Academic Journal

Contributions of the international plant science community to the fight against infectious diseases in humans—part 2:Affordable drugs in edible plants for endemic and re-emerging diseases

Subjects: endemic disease; molecular farming; oral delivery

  • Source: He , W , Baysal , C , Lobato Gómez , M , Huang , X , Alvarez , D , Zhu , C , Armario-Najera , V , Blanco Perera , A , Cerda Bennaser , P , Saba-Mayoral , A , Sobrino-Mengual , G , Vargheese , A ,

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Academic Journal

Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing

Subjects: Alternative Splicing; Animals; Apoptosis

  • Source: Li , J , Liu , F , Lv , Y , Sun , K , Zhao , Y , Reilly , J , Zhang , Y , Tu , J , Yu , S , Liu , X , Qin , Y , Huang , Y , Gao , P , Jia , D , Chen , X , Han , Y , Shu , X , Luo , D , Tang , Z & Liu

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Academic Journal

No detectable effect on visual responses using functional mri in a rodent model of a-synuclein expression

Subjects: Animals; Dependovirus; Disease Models

  • Source: Østergaard , F G , Skoven , C S , Wade , A R , Siebner , H R , Laursen , B , Christensen , K V & Dyrby , T B 2021 , ' No detectable effect on visual responses using functional mri in a rodent model

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Academic Journal

A Peek into the Plasmidome of Global Sewage

Subjects: Plasmids; Microbiome; Wastewater

  • Source: Kirstahler , P , Teudt , F , Otani , S , Aarestrup , F M & Pamp , S J 2021 , ' A Peek into the Plasmidome of Global Sewage ' , mSystems , vol. 6 , no. 3 , e00283-21 .

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Academic Journal

Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic Sulfotransferase from Fusarium graminearum PH-1

Subjects: combinatorial biosynthesis; Fusarium; phenolic sulfotransferase

  • Source: Xie , L , Xiao , D , Wang , X , Wang , C , Bai , J , Yue , Q , Yue , H , Li , Y , Molnár , I , Xu , Y & Zhang , L 2020 , ' Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic

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Academic Journal

Tumor Targeting by α v β 3 -Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking

Subjects: cyclic RGD nanoparticles; immune cell hitchhiking; intravital microscopy

  • Source: Sofias , A M , Toner , Y C , Meerwaldt , A E , van Leent , M M T , Soultanidis , G , Elschot , M , Gonai , H , Grendstad , K , Flobak , Å , Neckmann , U , Wolowczyk , C , Fisher , E L , Reiner , T ,

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Academic Journal

Whole-Body Atherosclerosis Imaging by Positron Emission Tomography/Magnetic Resonance Imaging:From Mice to Nonhuman Primates

Subjects: anomedicine; atherosclerosis; cardiovascular disease

  • Source: Calcagno , C , Pérez-Medina , C , Mulder , W J M & Fayad , Z A 2020 , ' Whole-Body Atherosclerosis Imaging by Positron Emission Tomography/Magnetic Resonance Imaging : From Mice to Nonhuman Primates

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Academic Journal

Multilayer network analysis unravels haulage vehicles as a hidden threat to the British swine industry

Subjects: disease control; epidemiology; infectious diseases

  • Source: Porphyre , T , Bronsvoort , B M D C , Gunn , G J & Correia-Gomes , C 2020 , ' Multilayer network analysis unravels haulage vehicles as a hidden threat to the British swine industry ' , Transboundary

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Academic Journal

Lactoferrin quantification in cattle faeces by ELISA

Subjects: Agriculture; Animals; Ecology

  • Source: Cooke , A S , Watt , K A , Albery , G F , Morgan , E R & Dungait , J A J 2020 , ' Lactoferrin quantification in cattle faeces by ELISA ' , PeerJ . https://doi.org/10.7717/peerj.8631

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Academic Journal

TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development

Subjects: Breast cancer; Context-dependent regulator; E-cadherin

  • Source: Cornelissen , L M , Drenth , A P , Van Der Burg , E , De Bruijn , R , Pritchard , C E J , Huijbers , I J , Zwart , W & Jonkers , J 2020 , ' TRPS1 acts as a context-dependent regulator of mammary

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Academic Journal

Transcription Factor 2I Regulates Neuronal Development via TRPC3 in 7q11.23 Disorder Models

Subjects: Animals; Axons/metabolism; Calcium/metabolism

  • Source: Deurloo , M H S , Turlova , E , Chen , W L , Lin , Y W , Tam , E , Tassew , N G , Wu , M , Huang , Y C , Crawley , J N , Monnier , P P , Groffen , A J A , Sun , H S , Osborne , L R & Feng , Z P 2019 ,

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Academic Journal

SALM1 controls synapse development by promoting F-actin/PIP2-dependent Neurexin clustering

Subjects: Actins/metabolism; Animals; Calcium-Binding Proteins/metabolism

  • Source: Brouwer , M , Farzana , F , Koopmans , F , Chen , N , Brunner , J W , Oldani , S , Li , K W , van Weering , J R , Smit , A B , Toonen , R F & Verhage , M 2019 , ' SALM1 controls synapse development by

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Academic Journal

Smart cancer nanomedicine

Subjects: Animals; Antineoplastic Agents/administration & dosage; Biomarkers

  • Source: van der Meel , R , Sulheim , E , Shi , Y , Kiessling , F , Mulder , W & Lammers , T 2019 , ' Smart cancer nanomedicine ' , Nature Nanotechnology , vol. 14 , no. 11 , pp. 1007–1017 .

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Academic Journal

On the relationship between dynamic contrast-enhanced ultrasound parameters and the underlying vascular architecture extracted from acoustic angiography

Subjects: Acoustic angiography; Cancer; Dispersion

  • Source: Panfilova , A , Shelton , S E , Caresio , C , van Sloun , R J G , Molinari , F , Wijkstra , H , Dayton , P A & Mischi , M 2019 , ' On the relationship between dynamic contrast-enhanced ultrasound

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Academic Journal

Activation of RyR2 by class I kinase inhibitors

Subjects: Animals; Dose-Response Relationship; Drug

  • Source: Chakraborty , A D , Gonano , L A , Munro , M L , Smith , L J , Thekkedam , C , Staudacher , V , Gamble , A B , Macquaide , N , Dulhunty , A F & Jones , P P 2019 , ' Activation of RyR2 by class I

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Academic Journal

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models

Subjects: Animals; Benzimidazoles/pharmacology; Breast Neoplasms/drug therapy

  • Source: Xue , Z , Vis , D J , Bruna , A , Sustic , T , van Wageningen , S , Batra , A S , Rueda , O M , Bosdriesz , E , Caldas , C , Wessels , L F A & Bernards , R 2018 , ' MAP3K1 and MAP2K4 mutations are

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Academic Journal

An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential

Subjects: Amino Acid Transport System y+/metabolism; Animals; Apoptosis

  • Source: Wang , L , Leite de Oliveira , R , Huijberts , S , Bosdriesz , E , Pencheva , N , Brunen , D , Bosma , A , Song , J-Y , Zevenhoven , J , Los-de Vries , G T , Horlings , H , Nuijen , B , Beijnen , J H

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Academic Journal

Integrating immunology and microfluidics for single immune cell analysis

Subjects: Cellular communication; Cellular heterogeneity; Immunoengineering

  • Source: Sinha , N , Subedi , N & Tel , J 2018 , ' Integrating immunology and microfluidics for single immune cell analysis ' , Frontiers in Immunology , vol. 9 , 2373 .

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Academic Journal

Notochordal cell matrix:An inhibitor of neurite and blood vessel growth?

Subjects: angiogenesis; intervertebral disc; neurogenesis

  • Source: de Vries , S A H , van Doeselaar , M , Meij , B P , Tryfonidou , M A & Ito , K 2018 , ' Notochordal cell matrix : An inhibitor of neurite and blood vessel growth? ' , Journal of Orthopaedic Research ,

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Academic Journal

Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice

Subjects: Animals; Antigens; Neoplasm/chemistry

  • Source: Rossin , R , Versteegen , R M , Wu , J , Khasanov , A , Wessels , H J , Steenbergen , E J , ten Hoeve , W , Janssen , H M , van Onzen , A H A M , Hudson , P J & Robillard , M S 2018 , ' Chemically

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Academic Journal

A microfluidics platform for combinatorial drug screening on cancer biopsies

Subjects: Animals; Antineoplastic Combined Chemotherapy Protocols/pharmacology; Biopsy

  • Source: Eduati , F , Utharala , R , Madhavan , D , Neumann , U P , Longerich , T , Cramer , T , Saez-Rodriguez , J & Merten , C A 2018 , ' A microfluidics platform for combinatorial drug screening on cancer

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Academic Journal

Find drugs that delay many diseases of old age

Subjects: Age Distribution; Aged; 80 and over

  • Source: Bellantuono , I , DeCabo , R , Ehninger , D , Fernandes , A , Howlett , S E , Müller , R , Potter , P , Tchkonia , T , Trendelenburg , A-U , Trejo , J L , Vandenbroucke , R , van Os , R & van Riel ,

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Academic Journal

Inhibiting inflammation with Myeloid cell-specific nanobiologics promotes organ transplant acceptance

Subjects: CD40; immunotherapy; innate immune memory

  • Source: Braza , M S , van Leent , M M T , Lameijer , M , Sanchez-Gaytan , B L , Arts , R J W , Pérez-Medina , C , Conde , P , Garcia , M R , Gonzalez-Perez , M , Brahmachary , M , Fay , F , Kluza , E ,

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Academic Journal

MRI based 3D finite element modelling to investigate deep tissue injury

Subjects: deep tissue injury; finite element modelling (FE); indentation test

  • Source: Traa , W A , van Turnhout , M C , Moerman , K M , Nelissen , J L , Nederveen , A J , Strijkers , G J , Bader , D L & Oomens , C W J 2018 , ' MRI based 3D finite element modelling to investigate deep

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Academic Journal

High Fibroblast Growth Factor 23 concentrations in experimental renal failure impair calcium handling in cardiomyocytes

Subjects: Calcium; cardiac; chronic kidney disease

  • Source: NIGRAM consortium 2018 , ' High Fibroblast Growth Factor 23 concentrations in experimental renal failure impair calcium handling in cardiomyocytes ' , Physiological Reports , vol. 6 , no. 7 , e13591 .

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Academic Journal

Sumoylation of Notch1 represses its target gene expression during cell stress

Subjects: Animals; COS Cells; Chlorocebus aethiops

  • Source: Antila , C J M , Rraklli , V , Blomster , H A , Dahlström , K M , Salminen , T A , Holmberg , J , Sistonen , L & Sahlgren , C M 2018 , ' Sumoylation of Notch1 represses its target gene expression

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Academic Journal

Pet owner and vet interactions: exploring the drivers of AMR

Subjects: antibiotic resistance; pets; vets

  • Source: Smith , M , King , C , Davis , M , Dickson , A , Park , J , Smith , F , Currie , K & Flowers , P 2018 , ' Pet owner and vet interactions: exploring the drivers of AMR ' , Antimicrobial Resistance and

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