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Academic Journal

Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions: relevance to class switch recombination

Subjects: Institute of Molecular Cancer Research; 570 Life sciences; biology

  • Source: Bregenhorn, Stephanie; Kallenberger, Lia; Artola-Borán, Mariela; Peña-Diaz, Javier; Jiricny, Josef (2016). Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions:

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Academic Journal

The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination

Subjects: Institute of Experimental Immunology; 570 Life sciences; biology

  • Source: Chahwan, Richard; van Oers, Johanna M M; Avdievich, Elena; Zhao, Chunfang; Edelmann, Winfried; Scharff, Matthew D; Roa, Sergio (2012). The ATPase activity of MLH1 is required to orchestrate DNA

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Academic Journal

The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination

Subjects: Institute of Experimental Immunology; 570 Life sciences; biology

  • Source: Ramachandran, Shaliny; Chahwan, Richard; Nepal, Rajeev M; Frieder, Darina; Panier, Stephanie; Roa, Sergio; Zaheen, Ahmad; Durocher, Daniel; Scharff, Matthew D; Martin, Alberto (2010). The RNF8/RNF168

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Academic Journal

BCL3-rearrangements in B-cell lymphoid neoplasms occur in two breakpoint clusters associated with different diseases

Subjects: Clinic for Oncology and Hematology; Institute of Pathology and Molecular Pathology; 610 Medicine & health

  • Source: Carbo-Meix, Anna; Guijarro, Francesca; Wang, Luojun; Grau, Marta; Royo, Romina; Frigola, Gerard; Playa-Albinyana, Heribert; Bühler, Marco M; Clot, Guillem; Duran-Ferrer, Marti; Lu, Junyan; Granada,

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Academic Journal

Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice

Subjects: Institute of Experimental Immunology; Translational Cancer Research; 570 Life sciences

  • Source: Wang, Shanzhi; Lee, Kyeryoung; Gray, Stephen; Zhang, Yongwei; Tang, Catherine; Morrish, Rikke B; Tosti, Elena; van Oers, Johanna; Amin, Mohammad Ruhul; Cohen, Paula E; MacCarthy, Thomas; Roa, Sergio;

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Academic Journal

Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

Subjects: Medical Clinic; 610 Medicine & health

  • Source: Ghraichy, Marie; von Niederhäusern, Valentin; Kovaltsuk, Aleksandr; Galson, Jacob D; Deane, Charlotte M; Trück, Johannes (2021). Different B cell subpopulations show distinct patterns in their IgH

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Academic Journal

RAD51 Inhibition Induces R-Loop Formation in Early G1 Phase of the Cell Cycle

Subjects: Institute of Molecular Cancer Research; 570 Life sciences; biology

  • Source: Nascakova, Zuzana; Boleslavska, Barbora; Urban, Vaclav; Oravetzova, Anna; Vlachova, Edita; Janscak, Pavel; Dobrovolna, Jana (2021). RAD51 Inhibition Induces R-Loop Formation in Early G1 Phase of the

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Academic Journal

IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms

Subjects: Clinic for Oncology and Hematology; 610 Medicine & health

  • Source: Nadeu, Ferran; Mas-de-Les-Valls, Rut; Navarro, Alba; Royo, Romina; Martín, Silvia; Villamor, Neus; Suárez-Cisneros, Helena; Mares, Rosó; Lu, Junyan; Enjuanes, Anna; Rivas-Delgado, Alfredo;

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Academic Journal

Epigenomic Modifications Mediating Antibody Maturation

Subjects: Institute of Experimental Immunology; 570 Life sciences; biology

  • Source: Sheppard, Emily C; Morrish, Rikke Brandstrup; Dillon, Michael J; Leyland, Rebecca; Chahwan, Richard (2018). Epigenomic Modifications Mediating Antibody Maturation. Frontiers in Immunology, 9:355.

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Academic Journal

Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes

Subjects: Institute of Experimental Immunology; 570 Life sciences; biology

  • Source: Schaetzlein, Sonja; Chahwan, Richard; Avdievich, Elena; Roa, Sergio; Wei, Kaichun; Eoff, Robert L; Sellers, Rani S; Clark, Alan B; Kunkel, Thomas A; Scharff, Matthew D; Edelmann, Winfried (2013).

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