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Academic Journal

Prolyl isomerization: A new PIN code for DSB repair

Subjects: Institute of Molecular Cancer Research; 570 Life sciences; biology

  • Source: Sartori, Alessandro A; Steger, Martin (2013). Prolyl isomerization: A new PIN code for DSB repair. Cell Cycle, 12(17):2717-2718.

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Academic Journal

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks

Subjects: Department of Molecular Mechanisms of Disease; 570 Life sciences; biology

  • Source: Rother, Magdalena B; Pellegrino, Stefania; Smith, Rebecca; Gatti, Marco; Meisenberg, Cornelia; Wiegant, Wouter W; Luijsterburg, Martijn S; Imhof, Ralph; Downs, Jessica A; Vertegaal, Alfred C O; Huet,

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Academic Journal

Harnessing DNA Double-Strand Break Repair for Cancer Treatment

Subjects: Institute of Molecular Cancer Research; 570 Life sciences; biology

  • Source: Trenner, Anika; Sartori, Alessandro A (2019). Harnessing DNA Double-Strand Break Repair for Cancer Treatment. Frontiers in Oncology, 9:1388.

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Academic Journal

H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours

Subjects: Institute of Molecular Cancer Research; 610 Medicine & health; 570 Life sciences

  • Source: Dibitetto, Diego; Liptay, Martin; Vivalda, Francesca; Dogan, Hülya; Gogola, Ewa; González Fernández, Martín; Duarte, Alexandra; Schmid, Jonas A; Decollogny, Morgane; Francica, Paola; Przetocka,

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Academic Journal

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas

Subjects: Dermatology Clinic; 610 Medicine & health

  • Source: Czyż, Małgorzata; Toma, Monika; Gajos-Michniewicz, Anna; Majchrzak, Kinga; Hoser, Grazyna; Szemraj, Janusz; Nieborowska-Skorska, Margaret; Cheng, Phil; Gritsyuk, Daniel; Levesque, Mitchell P;

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Academic Journal

Controlling DNA-end resection: an emerging task for ubiquitin and SUMO

Subjects: Institute of Molecular Cancer Research; 570 Life sciences; biology

  • Source: Himmels, Sarah-Felicitas; Sartori, Alessandro A (2016). Controlling DNA-end resection: an emerging task for ubiquitin and SUMO. Frontiers in Genetics, 7:152.

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Academic Journal

Controlling DNA-end resection: a new task for CDKs

Subjects: Institute of Molecular Cancer Research; 570 Life sciences; biology

  • Source: Ferretti, Lorenza P; Lafranchi, Lorenzo; Sartori, Alessandro A (2013). Controlling DNA-end resection: a new task for CDKs. Frontiers in Genetics, 4:99.

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Academic Journal

The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis

Subjects: Clinic for Gynecology; 610 Medicine & health

  • Source: de Marco Zompit, Mara; Esteban, Mònica Torres; Mooser, Clémence; Adam, Salomé; Rossi, Silvia Emma; Jeanrenaud, Alain; Leimbacher, Pia-Amata; Fink, Daniel; Shorrocks, Ann-Marie K; Blackford, Andrew

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Academic Journal

A stapled peptide mimetic of the CtIP tetramerization motif interferes with double-strand break repair and replication fork protection

Subjects: Institute of Molecular Cancer Research; 570 Life sciences; biology

  • Source: Kuster, Anika; Mozaffari, Nour L; Wilkinson, Oliver J; Wojtaszek, Jessica L; Zurfluh, Christina; Przetocka, Sara; Zyla, Dawid; von Aesch, Christine; Dillingham, Mark S; Williams, R Scott; Sartori,

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Academic Journal

Human CtIP: A 'double agent' in DNA repair and tumorigenesis

Subjects: Institute of Molecular Cancer Research; 570 Life sciences; biology

  • Source: Mozaffari, Nour L; Pagliarulo, Fabio; Sartori, Alessandro A (2021). Human CtIP: A 'double agent' in DNA repair and tumorigenesis. Seminars in Cell & Developmental

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