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Academic Journal

Inactivation of the tumor suppressor gene Apc synergizes with H. pylori to induce DNA damage in murine gastric stem and progenitor cells

Subjects: Institute of Molecular Cancer Research; Functional Genomics Center Zurich; Institute of Molecular Life Sciences

  • Source: He, Jiazhuo; Nascakova, Zuzana; Leary, Peter; Papa, Giovanni; Valenta, Tomas; Basler, Konrad; Müller, Anne (2023). Inactivation of the tumor suppressor gene Apc synergizes with H. pylori to induce

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Academic Journal

PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy

Subjects: Clinic for Oncology and Hematology; 610 Medicine & health; Myeloid Neoplasia

  • Source: Miller, Peter Grant; Sperling, Adam S; Mayerhofer, Christina; McConkey, Marie E; Ellegast, Jana Maria; Da Silva, Carmen; Cohen, Drew Nathaniel; Wang, Chuqi; Sharda, Azeem; Yan, Ni; Saha, Subha;

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Academic Journal

Dynamic In Vivo profiling of DNA damage and repair after radiotherapy using canine patients as a model

Subjects: Epidemiology; Biostatistics and Prevention Institute (EBPI); Institute of Veterinary Pathology

  • Source: Schulz, Nadine; Chaachouay, Hassan; Nytko, Katarzyna J; Weyland, Mathias S; Roos, Malgorzata; Füchslin, Rudolf M; Guscetti, Franco; Scheidegger, Stephan; Rohrer Bley, Carla (2017). Dynamic In Vivo

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Academic Journal

Biomolecular condensates at sites of DNA damage: More than just a phase

Subjects: Department of Molecular Mechanisms of Disease; 570 Life sciences; biology

  • Source: Spegg, Vincent; Altmeyer, Matthias (2021). Biomolecular condensates at sites of DNA damage: More than just a phase.

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Academic Journal

DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end joining

Subjects: Clinic for Oncology and Hematology; 610 Medicine & health

  • Source: Cabrini, Matteo; Roncador, Marco; Galbiati, Alessandro; Cipolla, Lina; Maffia, Antonio; Iannelli, Fabio; Sabbioneda, Simone; d'Adda di Fagagna, Fabrizio; Francia, Sofia (2021). DROSHA is recruited to

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