نتائج البحث

Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration

• Authors : Pearring, Jillian N.; San Agustin, Jovenal T.; Lobanova, Ekaterina S. ...

Subjects: Cellular and Molecular Physiology; Genetics and Genomics

• Source: PLoS genetics ; 13 ; 4 ; e1006740

تفاصيل العنوان

DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice

• Authors : Zheng, Shijie; Xiao, Lirong; Liu, Yu ...

Subjects: Biochemistry; Biophysics; and Structural Biology

• Source: Cell death and disease ; 9 ; 3 ; 310

تفاصيل العنوان

Update on Viral Gene Therapy Clinical Trials for Retinal Diseases

• Authors : Cheng, Shun-Yun; Punzo, Claudio;

Subjects: clinical trials; retinal degeneration; retinal gene therapy

• Source: Human gene therapy ; 33 ; 17-18 ; 865 ; 878 ; United States

تفاصيل العنوان

Modulation of Severity of RPGR-associated Retinal Degeneration in Mice due to Mutations in RPGR-interacting Proteins

• Authors : Li, Linjing; Kollu, Nageswara Rao; Ronquillo, Cecinio C.

Subjects: Retinitis Pigmentosa; Eye Diseases; Ophthalmology

تفاصيل العنوان

Ablation Of Raf-1 Kinase Inhibitory Protein (RKIP) Improves Photoreceptor Structure and Function in a Cep290-Mutant Mouse Model Of Severe Retinal Degeneration

• Authors : Subramanian, Balajikarthick; Anand, Manisha; Khanna, Hemant

Subjects: Cellular and Molecular Physiology; Eye Diseases; Ophthalmology

تفاصيل العنوان

Oxidative Stress Resistance 1 Gene Therapy Retards Neurodegeneration in the rd1 Mutant Mouse Model of Retinopathy

• Authors : Sahu, Bhubanananda; Moreno-Leon, Laura; Zhang, Wei ...

Subjects: oxidative stress; gene therapy; retinal degeneration

• Source: Investigative ophthalmology and visual science ; 62 ; 12 ; 8

تفاصيل العنوان

Tsc2 knockout counteracts ubiquitin-proteasome system insufficiency and delays photoreceptor loss in retinitis pigmentosa

• Authors : Wang, Yixiao; Punzo, Claudio; Ash, John D ...

Subjects: mTORC1; photoreceptor; proteasome

• Source: Proceedings of the National Academy of Sciences of the United States of America ; 119 ; 11 ; e2118479119 ; United States

تفاصيل العنوان

Preventing Neurodegeneration by Controlling Oxidative Stress: The Role of OXR1

• Authors : Volkert, Michael R.; Crowley, David J.; Department of Microbiology and Physiological Systems

Subjects: OXR1; gene therapy; neurodegeneration

• Source: Frontiers in neuroscience ; 14 ; 611904

تفاصيل العنوان

Structural but Not Functional Alterations in Cones in the Absence of the Retinal Disease Protein Retinitis Pigmentosa 2 (RP2) in a Cone-Only Retina

• Authors : Li, Linjing; Rao, Kollu N.; Khanna, Hemant ...

Subjects: cilia; ciliopathies; cone

• Source: Frontiers in genetics ; 10 ; 323

تفاصيل العنوان

Gene Therapy Using a miniCEP290 Fragment Delays Photoreceptor Degeneration in a Mouse Model of Leber Congenital Amaurosis

• Authors : Zhang, Wei; Li, Linjing; Su, Qin ...

Subjects: LCA; cilia; ciliopathies

• Source: Human gene therapy ; 29 ; 1 ; 42-50

تفاصيل العنوان