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A quantitative AOP of mitochondrial toxicity based on data from three cell lines

• Authors : Tebby, Cleo; Gao, Wang; Delp, Johannes

Subjects: Quantitative adverse outcome pathway; Mitochondrial toxicity; In vitro

• Source: Toxicology in Vitro. Elsevier. 2022, 81, 105345. ISSN 0887-2333. eISSN 1879-3177. Available under: doi:10.1016/j.tiv.2022.105345

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Acute toxicity of the fungicide captan to honey bees and mixed evidence for synergism with the insecticide thiamethoxam

• Authors : De Souza, Daiana; Urbanowicz, Christine; Ng, Wee Hao

Subjects: ddc:570

• Source: Scientific Reports. Springer. 2024, 14(1), 15709. eISSN 2045-2322. Verfügbar unter: doi:10.1038/s41598-024-66248-x

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Comparison of points of departure between subchronic and chronic toxicity studies on food additives, food contaminants and natural food constituents

• Authors : Guth, Sabine; Roth, Angelika; Engeli, Barbara

Subjects: Subchronic toxicity studies; Chronic toxicity studies; Extrapolation factor

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4.2 million and counting… The animal toll for REACH systemic toxicity studies

• Authors : Knight, Jean; Hartung, Thomas; Rovida, Costanza

Subjects: ddc:570

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Basic concepts of mixture toxicity and relevance for risk evaluation and regulation

• Authors : Bloch, Denise; Diel, Patrick; Epe, Bernd

Subjects: ddc:570

• Source: Archives of Toxicology. Springer. 2023, 97, pp. 3005-3017. ISSN 0340-5761. eISSN 1432-0738. Available under: doi:10.1007/s00204-023-03565-6

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Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib

• Authors : Shaker, Mohamed E.; Gomaa, Hesham A. M.; Hazem, Sara H.

Subjects: alpelisib; phosphatidylinositol 3-kinase; acetaminophen

• Source: Frontiers in Pharmacology. Frontiers. 2023, 14, 1212771. eISSN 1663-9812. Available under: doi:10.3389/fphar.2023.1212771

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Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells

• Authors : Ramirez, Tzutzuy; Strigun, Alexander; Verlohner, Andreas

Subjects: Metabolomics; Liver toxicity; In vitro

• Source: Archives of toxicology. 2018, 92(2), pp. 893-906. ISSN 0340-5761. eISSN 1432-0738. Available under: doi:10.1007/s00204-017-2079-6

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Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage

• Authors : Del Rio Oliva, Marta; Basler, Michael

Subjects: ddc:570

• Source: Cell Death & Disease. Springer Nature. 2022, 13(12), 1015. eISSN 2041-4889. Available under: doi:10.1038/s41419-022-05461-w

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Neurodevelopmental toxicity assessment of flame retardants using a human DNT in vitro testing battery

• Authors : Klose, Jördis; Pahl, Melanie; Bartmann, Kristina

Subjects: Developmental neurotoxicity; Flame retardants; Human cell–based testing battery

• Source: Cell biology and toxicology. Springer Science. 2022, 38(5), pp. 781-807. ISSN 0742-2091. eISSN 1573-6822. Available under: doi:10.1007/s10565-021-09603-2

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Toxicity and Starvation Induce Major Trophic Isotope Variation in Daphnia Individuals : A Diet Switch Experiment Using Eight Phytoplankton Species of Differing Nutritional Quality

• Authors : Helmer, Michelle; Helmer, Desiree; Martin-Creuzburg, Dominik

Subjects: stable isotopes; cyanobacteria; turnover-rates

• Source: Biology. MDPI. 2022, 11(12), 1816. eISSN 2079-7737. Available under: doi:10.3390/biology11121816

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