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Academic Journal

Pharmacokinetics of a hepatic stellate cell-targeted doxorubicin construct in bile duct-ligated rats

Subjects: liver fibrosis; drug targeting; hepatic stellate cell

  • Source: Greupink , R , Reker-Smit , C , Proost , J H , Weemaes , A V L , de Hooge , M , Poelstra , K & Beljaars , L 2007 , ' Pharmacokinetics of a hepatic stellate cell-targeted doxorubicin construct in bile

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Academic Journal

Targeting 15d-prostaglandin J(2) to hepatic stellate cells:Two options evaluated

Subjects: antifibrotic drugs; drug targeting; hepatic stellate cells

  • Source: Hagens , W I , Mattos Pinto , A , Greupink , R , de Jager-Krikken , A , Reker-Smit , C , van Loenen - Weemaes , A , Gouw , A S H , Poelstra , K & Beljaars , L 2007 , ' Targeting 15d-prostaglandin J(2)

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Academic Journal

Increased Liver Uptake and Reduced Hepatic Stellate Cell Activation with a Cell-Specific Conjugate of the Rho-kinase Inhibitor Y27632

Subjects: drug targeting; insulin-like growth factor II receptor; kinase inhibitor

  • Source: van Beuge , M M , Prakash , J , Lacombe , M , Post , E , Reker-Smit , C , Beljaars , L & Poelstra , K 2011 , ' Increased Liver Uptake and Reduced Hepatic Stellate Cell

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Academic Journal

Angiotensin II Protects Primary Rat Hepatocytes against Bile Salt-Induced Apoptosis

Subjects: ENDOPLASMIC-RETICULUM STRESS; HEPATIC STELLATE CELLS; ACID-INDUCED APOPTOSIS

  • Source: Karimian , G , Buist-Homan , M , Mikus , B , Henning , R H , Faber , K N & Moshage , H 2012 , ' Angiotensin II Protects Primary Rat Hepatocytes against Bile Salt-Induced Apoptosis ' , PLoS ONE , vol.

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Academic Journal

The I kappa B kinase inhibitor ACHP strongly attenuates TGF beta 1-induced myofibroblast formation and collagen synthesis

Subjects: fibrosis; collagen; myofibroblasts

  • Source: Mia , M M & Bank , R A 2015 , ' The I kappa B kinase inhibitor ACHP strongly attenuates TGF beta 1-induced myofibroblast formation and collagen synthesis ' , Journal of cellular and molecular medicine

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Academic Journal

Melatonin suppresses activation of hepatic stellate cells through ROR alpha-mediated inhibition of 5-lipoxygenase

Subjects: 5-lipoxygenase; hepatic stellate cell; hepatic stellate cell activation

  • Source: Shajari , S , Laliena , A , Heegsma , J , Jesus Tunon , M , Moshage , H & Faber , K N 2015 , ' Melatonin suppresses activation of hepatic stellate cells through ROR alpha-mediated inhibition of

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Academic Journal

Targeted Therapies in Liver Fibrosis:Combining the Best Parts of Platelet-Derived Growth Factor BB and Interferon Gamma

Subjects: liver fibrosis; drug targeting; THERAPY

  • Source: van Dijk , F , Olinga , P , Poelstra , K & Beljaars , L 2015 , ' Targeted Therapies in Liver Fibrosis : Combining the Best Parts of

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Academic Journal

Inflammatory glycoproteins in cardiometabolic disorders, autoimmune diseases and cancer

Subjects: Biomarker; Inflammation; Glycan

  • Source: Connelly , M A , Gruppen , E G , Otvos , J D & Dullaart , R P F 2016 , ' Inflammatory glycoproteins in cardiometabolic disorders, autoimmune diseases and cancer ' , Clinica chimica acta , vol. 459 ,

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Academic Journal

Liver fibrosis in 2015:Crucial steps towards an effective treatment

Subjects: Humans; Liver Cirrhosis; Macrophages

  • Source: Poelstra , K 2016 , ' Liver fibrosis in 2015 : Crucial steps towards an effective treatment ' , Nature Reviews Gastroenterology &

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Academic Journal

Receptor-specific TRAIL as a means to achieve targeted elimination of activated hepatic stellate cells

Subjects: Liver fibrosis; hepatic stellate cell; receptor-specific TRAIL

  • Source: Arabpour , M , Cool , R , Faber , K N , Quax , W J & Haisma , H J 2017 , ' Receptor-specific TRAIL as a means to achieve targeted elimination of activated hepatic stellate cells ' , Journal of Drug

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