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Academic Journal

Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion-Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study

Subjects: TELOMERASE INHIBITOR IMETELSTAT; EXPRESSION; HTERT

  • Source: Steensma , D P , Fenaux , P , Van Eygen , K , Raza , A , Santini , V , Germing , U , Font , P , Diez-Campelo , M , Thepot , S , Vellenga , E , Patnaik , M M , Jang , J H , Varsos , H , Bussolari , J ,

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Academic Journal

CREB signaling activity correlates with differentiation and survival in medulloblastoma

Subjects: ELEMENT-BINDING PROTEIN; CAMP; TRANSCRIPTION

  • Source: Armandari , I , Zomerman , W W , Plasschaert , S L A , Smit , M J , Martini , T E , Magalhaes , E S D C , Hogeling , S M , Rozema-Huizinga , G C , Lourens , H J , Meeuwsen-de Boer , T G J , Scherpen ,

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Academic Journal

Insulin-like growth factor 1 of wild vertebrates in a life-history context

Subjects: Adaptation; Fitness; Hormone

  • Source: Lodjak , J & Verhulst , S 2020 , ' Insulin-like growth factor 1 of wild vertebrates in a life-history context ' , Molecular and Cellular Endocrinology , vol. 518 , 110978 .

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Academic Journal

Genetic profiling for disease stratification in chronic obstructive pulmonary disease and asthma

Subjects: asthma; chronic obstructive pulmonary disease; whole exome sequencing

  • Source: Rathnayake , S N H , Van den Berge , M & Faiz , A 2019 , ' Genetic profiling for disease stratification in chronic obstructive pulmonary disease and asthma ' , Current Opinion in Pulmonary Medicine ,

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Academic Journal

Telomerase regulation by the Pif1 helicase:a length-dependent effect?

Subjects: Pif1; Telomeres; Telomerase

  • Source: Stinus , S , Paeschke , K & Chang , M 2018 , ' Telomerase regulation by the Pif1 helicase : a length-dependent effect? ' , Current Genetics , vol. 64 , no. 2 , pp.

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Academic Journal

ETS1, nucleolar and non-nucleolar TERT expression in nevus to melanoma progression

Subjects: TERT; ETS1; melanoma

  • Source: Kohli , J S , Mir , H , Wasif , A , Chong , H , Akhras , V , Kumar , R , Nagore , E & Bennett , D C 2017 , ' ETS1, nucleolar and non-nucleolar TERT expression in nevus to melanoma progression ' ,

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Academic Journal

The many facets of homologous recombination at telomeres

Subjects: homologous recombination; telomeres; alternative lengthening of telomeres

  • Source: Claussin , C & Chang , M 2015 , ' The many facets of homologous recombination at telomeres ' , Microbial Cell , vol. 2 , no. 9 , pp. 308-321 . https://doi.org/10.15698/mic2015.09.224

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Academic Journal

Enhanced microglial pro-inflammatory response to lipopolysaccharide correlates with brain infiltration and blood-brain barrier dysregulation in a mouse model of telomere shortening

Subjects: aging; blood-brain barrier; microglia

  • Source: Raj , D D A , Moser , J , van der Pol , S M A , van Os , R P , Holtman , I R , Brouwer , N , Oeseburg , H , Schaafsma , W , Wesseling , E M , Dunnen, den , W , Biber , K P H , de Vries , H E , Eggen ,

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Academic Journal

Measuring telomere length and telomere dynamics in evolutionary biology and ecology

Subjects: DNA extraction; single telomere length analysis; senescence

  • Source: Nussey , D H , Baird , D , Barrett , E , Boner , W , Fairlie , J , Gemmell , N , Hartmann , N , Horn , T , Haussmann , M , Olsson , M , Turbill , C , Verhulst , S , Zahn , S & Monaghan , P 2014 , '

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