نتائج البحث

Metabolic Dysfunction-Associated Steatotic Liver Disease in a Dish:Human Precision-Cut Liver Slices as a Platform for Drug Screening and Interventions

• Authors : Li, Mei; Larsen, Frederik T; van den Heuvel, Marius C

Subjects: Humans; Drug Evaluation; Preclinical

• Source: Li , M , Larsen , F T , van den Heuvel , M C , Gier , K , Gorter , A R , Oosterhuis , D , Bijzet , J , de Meijer , V E , Ravnskjaer , K , Nagelkerke , A & Olinga , P 2024 , ' Metabolic

تفاصيل العنوان

Patient-derived parathyroid organoids as a tracer and drug-screening application model

• Authors : Noltes, Milou E.; Sondorp, Luc H.J.; Kracht, Laura

Subjects: drug screening; endocrine diseases; hyperparathyroidism

• Source: Noltes , M E , Sondorp , L H J , Kracht , L , Antunes , I F , Wardenaar , R , Kelder , W , Kemper , A , Szymanski , W , Zandee , W T , Jansen , L , Brouwers , A H , Coppes , R P & Kruijff , S 2022 , '

تفاصيل العنوان

FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes

• Authors : de Poel, E; Spelier, S; Hagemeijer, M C

Subjects: Humans; Cystic Fibrosis/drug therapy; Cystic Fibrosis Transmembrane Conductance Regulator/genetics

• Source: de Poel , E , Spelier , S , Hagemeijer , M C , van Mourik , P , Suen , S W F , Vonk , A M , Brunsveld , J E , Ithakisiou , G N , Kruisselbrink , E , Oppelaar , H , Berkers , G , de Winter de Groot , K

تفاصيل العنوان

Drug screening and high throughput in three-dimensional lung models

• Authors : Kistemaker, Loes E.M.; Gosens, Reinoud

Subjects: COPD; drug discovery; fibrosis

• Source: Kistemaker , L E M & Gosens , R 2022 , Drug screening and high throughput in three-dimensional lung models . in 3D Lung Models for

تفاصيل العنوان

Expert Discussion of the Role of Rate Constant Versus Clearance Approaches to Define Drug Pharmacokinetics: Theoretical and Clinical Considerations

• Authors : Martinez, Marilyn N.; Jelliffe, Roger W.; Proost, Johannes H.

Subjects: Clearance; Discussion; Parameterization

• Source: Martinez , M N , Jelliffe , R W & Proost , J H 2020 , ' Expert Discussion of the Role of Rate Constant Versus Clearance Approaches to Define Drug Pharmacokinetics:

تفاصيل العنوان

How does a researcher choose the best rodent model for their Alzheimer's disease drug discovery study?

• Authors : Van Dam, Debby; De Deyn, Peter Paul

Subjects: Alzheimer?s disease; rodent model; drug screening

• Source: Van Dam , D & De Deyn , P P 2019 , ' How does a researcher choose the best rodent model for their Alzheimer's disease drug discovery study? ' , Expert Opinion on

تفاصيل العنوان

Hydrazine in the Ugi Tetrazole Reaction

• Authors : Patil, Pravin; Zhang, Ji; Kurpiewska, Katarzyna

Subjects: hydrazine; isocyanides; multicomponent reaction

• Source: Patil , P , Zhang , J , Kurpiewska , K , Kalinowska-Tłuścik , J & Dömling , A 2016 , ' Hydrazine in the Ugi Tetrazole Reaction ' , Synthesis , vol. 48 , no. 8 , pp. 1122-1130 .

تفاصيل العنوان

Preservation of the immunogenicity of dry-powder influenza H5N1 whole inactivated virus vaccine at elevated storage temperatures

• Authors : Geeraedts, Felix; Saluja, Vinay; ter Veer, Wouter

Subjects: Freeze-drying; Inulin; Pandemic influenza

• Source: Geeraedts , F , Saluja , V , ter Veer , W , Amorij , J-P , Frijlink , H W , Wilschut , J , Hinrichs , W L J & Huckriede , A 2010 , ' Preservation of the immunogenicity of dry-powder influenza H5N1

تفاصيل العنوان

Investigations into the stabilisation of drugs by sugar glasses:II: Delivery of an inulin-stabilised alkaline phosphatase in the intestinal lumen via the oral route

• Authors : Eriksson, H.J.C.; Verweij, W.R.; Poelstra, K.

Subjects: Oral administration; Proteins; Sugar glass

• Source: Eriksson , H J C , Verweij , W R , Poelstra , K , Hinrichs , W L J , de Jong , G J , Somsen , G W & Frijlink , H W 2003 , ' Investigations into the stabilisation of drugs by sugar glasses : II:

تفاصيل العنوان

Unraveling MASLD: Insights from Ex vivo Models

• Authors : Li, Mei

• Source: Li , M 2024 , ' Unraveling MASLD: Insights from Ex vivo Models ' , Doctor of Philosophy , University of Groningen , [Groningen] . https://doi.org/10.33612/diss.1094088759

تفاصيل العنوان