نتائج البحث

Novel mechanisms of efflux-mediated levofloxacin resistance and reduced amikacin susceptibility in Stenotrophomonas maltophilia

• Authors : Dulyayangkul, Punyawee; Calvopina, Karina A; Heesom, Kate J

• Source: Dulyayangkul , P , Calvopina , K A , Heesom , K J & Avison , M B 2020 , ' Novel mechanisms of efflux-mediated levofloxacin resistance and reduced amikacin susceptibility in

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Mutations in Ribosomal Protein RplA or Treatment with Ribosomal Acting Antibiotics Activate Production of Aminoglycoside Efflux Pump SmeYZ in Stenotrophomonas maltophilia

• Authors : Calvopiña, Karina; Dulyayangkul, Punyawee; Avison, Matthew B

• Source: Calvopiña , K , Dulyayangkul , P & Avison , M B 2020 , ' Mutations in Ribosomal Protein RplA or Treatment with Ribosomal Acting Antibiotics Activate Production of Aminoglycoside Efflux Pump SmeYZ in

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TonB dependent uptake of β-lactam antibiotics in the opportunistic human pathogen Stenotrophomonas maltophilia

• Authors : Calvopiña, Karina; Dulyayangkul, Punyawee; Heesom, Kate J

Subjects: antibiotic resistance; ceftazidime; fluoroquinolones

• Source: Calvopiña , K , Dulyayangkul , P , Heesom , K J & Avison , M B 2019 , ' TonB dependent uptake of β-lactam antibiotics in the opportunistic human pathogen

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Disruption of mpl Activates β-Lactamase Production in Stenotrophomonas maltophilia and Pseudomonas aeruginosa Clinical Isolates

• Authors : Calvopina Tapia, Karina; Avison, Matthew

Subjects: beta-lactamases; ceftazidime; regulation

• Source: Calvopina Tapia , K & Avison , M 2018 , ' Disruption of mpl Activates β-Lactamase Production in Stenotrophomonas maltophilia and

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Structural/mechanistic insights into the efficacy of nonclassical β-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates

• Authors : Calvopina Tapia, Karina; Hinchliffe, Philip; Brem, Jürgen

• Source: Calvopina Tapia , K , Hinchliffe , P , Brem , J , Heesom , K J , Johnson , S , Cain , R , Lohans , C T , Fishwick , C W G , Schofield , C J , Spencer , J & Avison , M B 2017 , ' Structural/mechanistic

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Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates

• Authors : Calvopiña, Karina; Umland, Klaus-Daniel; Rydzik, Anna M

• Source: Calvopiña , K , Umland , K-D , Rydzik , A M , Hinchliffe , P , Brem , J , Spencer , J , Schofield , C J & Avison , M B 2016 , ' Sideromimic Modification of Lactivicin Dramatically Increases Potency

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Exploring the views of infection consultants in England on a novel delinked funding model for antimicrobials:the SMASH study

• Authors : Baltas, Ioannis; Gilchrist, Mark; Koutoumanou, Eirini

• Source: Baltas , I , Gilchrist , M , Koutoumanou , E , Gibani , M M , Meiring , J E , Otu , A , Hettle , D , Thompson , A , Price , J R , Crepet , A , Atomode , A , Crocker-Buque , T , Spinos , D , Guyver , H

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Interactions of hydrolyzed β-lactams with the L1 metallo-β-lactamase:Crystallography supports stereoselective binding of cephem/carbapenem products

• Authors : Hinchliffe, Philip; Calvopiña, Karina; Rabe, Patrick

• Source: Hinchliffe , P , Calvopiña , K , Rabe , P , Mojica , M F , Schofield , C J , Dmitrienko , G I , Bonomo , R A , Vila , A J & Spencer , J 2023 , ' Interactions of hydrolyzed β-lactams with the L1

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Crystallography and QM/MM Simulations Identify Preferential Binding of Hydrolyzed Carbapenem and Penem Antibiotics to the L1 Metallo-β-Lactamase in the Imine Form

• Authors : Twidale, Rebecca M; Hinchliffe, Philip; Spencer, James

• Source: Twidale , R M , Hinchliffe , P , Spencer , J & Mulholland , A J 2021 , ' Crystallography and QM/MM Simulations Identify Preferential Binding of Hydrolyzed Carbapenem and Penem Antibiotics to the L1

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Molecular Basis of Class A β-lactamase Inhibition by Relebactam

• Authors : Tooke, Catherine; Hinchliffe, Philip; Pauline, Lang

Subjects: antibiotic resistance; diazabicyclooctane; avibactam

• Source: Tooke , C , Hinchliffe , P , Pauline , L , Mulholland , A , Brem , J , Schofield , C J & Spencer , J 2019 , ' Molecular Basis of Class A β-lactamase Inhibition by Relebactam ' , Antimicrobial Agents

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