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Academic Journal

Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx

Subjects: /dk/atira/pure/core/keywords/heart_SRI; name=Bristol Heart Institute

  • Source: Crompton , M , Ferguson , J K , Ramnath , R D , Onions , K L , Ogier , A S , Gamez , M , Down , C J , Skinner , L , Wong , K H , Dixon , L K , Sutak , J , Harper , S J , Pontrelli , P , Gesualdo , L ,

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Academic Journal

Aldosterone induces albuminuria via matrix metalloproteinase–dependent damage of the endothelial glycocalyx

Subjects: /dk/atira/pure/core/keywords/heart_SRI; name=Bristol Heart Institute; aldosterone

  • Source: Butler , M J , Ramnath , R , Kadoya , H , Desposito , D , Riquier-Brison , A , Ferguson , J K , Onions , K L , Ogier , A S , ElHegni , H , Coward , R J , Welsh , G I , Foster , R R , Peti-Peterdi , J

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Academic Journal

Genetic association of albuminuria with cardiometabolic disease and blood pressure

Subjects: albuminuria; urine albumin excretion; urine albumin:creatinine ratio

  • Source: Haas , M E , Aragam , K G , Emdin , C , Bick , A G , Hemani , G & Davey Smith , G & Kathiresan , S 2018 , ' Genetic association of albuminuria with cardiometabolic

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Academic Journal

DBA2J db/db mice are susceptible to early albuminuria and glomerulosclerosis that correlates with systemic insulin resistance

  • Source: Østergaard , M V , Ribeiro Pinto , V , Stevenson , K , Worm , J , Fink , L N & Coward , R 2017 , ' DBA2J db/db mice are susceptible to early albuminuria and

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Academic Journal

Role of foetal kidney size on kidney function in childhood:the born in bradford cohort renal study

Subjects: Child; Humans; Infant

  • Source: Ziauddeen , N , Jeffrey , R F , Waiblinger , D , Fraser , S D , Alwan , N A , Yuen , H M , Azad , R , Mason , D , Wright , J , Coward , R J & Roderick , P J 2023 , ' Role of foetal kidney size on

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Academic Journal

Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function

Subjects: Diabetic nephropathy; insulin signaling; Adriamycin nephropathy

  • Source: Hurcombe , J , Lay , A , Ni , L , Barrington , F , Woodgett , J R , Quaggin , S E , Welsh , G & Coward , R 2019 , ' Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular

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Academic Journal

The Evolving Importance of Insulin Signaling in Podocyte Health and Disease.

Subjects: Podocyte; insulin signaling; diabetic kidney disease (DKD)

  • Source: Lay , A C & Coward , R J M 2018 , ' The Evolving Importance of Insulin Signaling in Podocyte Health and Disease. ' , Frontiers in Endocrinology , vol. 9 , 693 .

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Academic Journal

The Adolescent Cardio-Renal Intervention Trial (AdDIT):retinal vascular geometry and renal function in adolescents with type 1 diabetes

Subjects: Adolescent; Albumins/analysis; Albuminuria/physiopathology

  • Source: 2018 , ' The Adolescent Cardio-Renal Intervention Trial (AdDIT) : retinal vascular geometry and renal function in adolescents with type 1 diabetes ' , Diabetologia , vol. 61 , no. 4 , pp. 968-976 .

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Academic Journal

Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

Subjects: APOL1; podocytes; albuminuria

  • Source: Beckerman , P , Bi-Karchin , J , Park , A S D , Qiu , C , Dummer , P D , Soomro , I , Boustany-Kari , C M , Pullen , S S , Miner , J H , Hu , C-A A , Rohacs , T , Inoue , K , Ishibe , S , Saleem , M ,

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Academic Journal

A novel assay provides sensitive measurement of physiologically relevant changes in albumin permeability in isolated human and rodent glomeruli

Subjects: /dk/atira/pure/core/keywords/heart_SRI; name=Bristol Heart Institute; albuminuria

  • Source: Desideri , S , Onions , K L , Qiu , Y , Ramnath , R D , Butler , M J , Neal , C R , King , M L R , Salmon , A E , Saleem , M A , Welsh , G I , Michel , C C , Satchell , S C , Salmon , A H J & Foster ,

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