نتائج البحث

Two-substrate enzyme engineering using small libraries that combine the substrate preferences from two different variant lineages

• Authors : Mukhopadhyay, Arka; Karu, Kersti; Dalby, Paul A

Subjects: Mutagenesis; Site-Directed; Escherichia coli

• Source: Scientific Reports , 14 , Article 1287. (2024)

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Surface plasmon resonance using the catalytic domain of soluble guanylate cyclase allows the detection of enzyme activators.

• Authors : Mota, F; Allerston, CK; Hampden-Smith, K

Subjects: Biophysical techniques; Enzyme activators; Nitric oxide

• Source: Bioorg Med Chem Lett , 24 (4) pp. 1075-1079. (2014)

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Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation

• Authors : Manzoni, C; Mamais, A; Dihanich, S

Subjects: Autophagy; C-terminal of ROC; COR

• Source: Biochemical and Biophysical Research Communications , 441 (4) pp. 862-866. (2013)

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Rational substrate and enzyme engineering of transketolase for aromatics

• Authors : Payongsri, P; Steadman, D; Strafford, J

Subjects: Benzoic Acid; Catalytic Domain; Escherichia coli

• Source: Organic & Biomolecular Chemistry , 10 (45) 9021 - 9029. (2012)

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Directed evolution to re-adapt a co-evolved network within an enzyme.

• Authors : Strafford, J; Payongsri, P; Hibbert, EG

Subjects: Acetaldehyde; Aldehydes; Catalytic Domain

• Source: Journal of Biotechnology , 157 (1) 237 - 245. (2012)

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Functional cdc25C dual-specificity phosphatase is required for S-phase entry in human cells

• Authors : Turowski, P; Franckhauser, C; Morris, MC

Subjects: MAMMALIAN-CELLS; CYCLIN-A; DEPENDENT PHOSPHORYLATION

• Source: MOL BIOL CELL , 14 (7) 2984 - 2998. (2003)

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Ancient Loss of Catalytic Selenocysteine Spurred Convergent Adaptation in a Mammalian Oxidoreductase

• Authors : Rees, Jasmin; Sarangi, Gaurab; Cheng, Qing ...

Subjects: selenocysteine; convergent; selenoprotein

• Source: Genome Biology and Evolution , 16 (3) , Article evae041. (2024)

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Structural and functional basis of protein phosphatase 5 substrate specificity

• Authors : Oberoi, J; Dunn, DM; Woodford, MR

Subjects: Hsp90; PP5; Cdc37

• Source: Proceedings of the National Academy of Sciences of the United States of America , 113 (32) pp. 9009-9014. (2016)

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The SH2 Domain Regulates c-Abl Kinase Activation by a Cyclin-Like Mechanism and Remodulation of the Hinge Motion

• Authors : Dölker, N; Górna, MW; Sutto, L

• Source: Plos Computational Biology (10) , Article e1003863. (2014)

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Structural mass spectrometry decodes domain interaction and dynamics of the full-length Human Histone Deacetylase 2

• Authors : Soloviev, Zoja; Bullock, Joshua MA; James, Juliette MB

Subjects: Crosslinking; Human Histone Deacetylase 2 (HDAC2); Intrinsically-disordered proteins

• Source: Biochimica et Biophysica Acta - Proteins and Proteomics , 1870 (3) , Article 140759. (2022)

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