نتائج البحث

Expanded CAG/CTG repeats resist gene silencing mediated by targeted epigenome editing.

• Authors : Yang, B.; Borgeaud, A.C.; Buřičová, M.

• Source: Human molecular genetics, vol. 31, no. 3, pp. 386-398

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The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing.

• Authors : Degrauwe, N.; Schlumpf, T.B.; Janiszewska, M.

Subjects: Base Sequence; Brain Neoplasms/genetics; Brain Neoplasms/pathology

• Source: Cell reports, vol. 15, no. 8, pp. 1634-1647

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MGMT gene silencing and benefit from temozolomide in glioblastoma.

• Authors : Hegi, M.E.; Diserens, A.C.; Gorlia, T.

Subjects: Antineoplastic Agents; Alkylating/therapeutic use; Brain Neoplasms/drug therapy

• Source: New England Journal of Medicine, vol. 352, no. 10, pp. 997-1003

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MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status.

• Authors : Bady, P.; Sciuscio, D.; Diserens, A.C.

• Source: Acta Neuropathologica, vol. 124, no. 4, pp. 547-560

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Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy.

• Authors : Seifinejad, A.; Ramosaj, M.; Shan, L.

Subjects: Mice; Animals; Orexins/metabolism

• Source: Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 19, pp. e2220911120

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Erratum to: MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status.

• Authors : Bady, P.; Sciuscio, D.; Diserens, A.C.

• Source: Acta Neuropathologica, vol. 126, no. 1, pp. 159

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tRNA 2'-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila.

• Authors : Angelova, M.T.; Dimitrova, D.G.; Da Silva, B.

Subjects: Animals; Drosophila melanogaster/genetics; Gene Expression Regulation/genetics

• Source: Nucleic acids research, vol. 48, no. 4, pp. 2050-2072

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Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation.

• Authors : Hämälistö, S.; Stahl, J.L.; Favaro, E.

Subjects: Animals; Cathepsin B/antagonists & inhibitors; Cathepsin B/genetics

• Source: Nature communications, vol. 11, no. 1, pp. 229

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A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers.

• Authors : Pisignano, G.; Napoli, S.; Magistri, M.

Subjects: Alleles; Antigens; CD

• Source: Nature communications, vol. 8, pp. 15622

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Gene transfer engineering for astrocyte-specific silencing in the CNS.

• Authors : Merienne, N.; Delzor, A.; Viret, A.

Subjects: Animals; Astrocytes/physiology; Central Nervous System/cytology

• Source: Gene Therapy, vol. 22, no. 10, pp. 830-839

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