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Academic Journal

The prFMNH 2 -binding chaperone LpdD assists UbiD decarboxylase activation

Subjects: UbiD decarboxylase; prFMN; chaperone

  • Source: Gahloth , D , Fisher , K , Marshall , S & Leys , D 2024 , ' The prFMNH 2 -binding chaperone LpdD assists UbiD decarboxylase activation ' , Journal of Biological Chemistry , vol. 300 , no. 2 , 105653 .

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Academic Journal

Aspergillus fumigatus mitogen-activated protein kinase MpkA is involved in gliotoxin production and self-protection

Subjects: Humans; Aspergillus fumigatus/metabolism; Gliotoxin/metabolism

  • Source: Alves de Castro , P , Figueiredo Pinzan , C , Dos Reis , T F , Valero , C , Van Rhijn , N , Menegatti , C , de Freitas Migliorini , I L , Bromley , M , Fleming , A B , Traynor , A M , Sarikaya-Bayram

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Academic Journal

Identification of eczema clusters and their association with filaggrin and atopic comorbidities:analysis of five birth cohorts

Subjects: Adolescent; Child; Preschool

  • Source: Haider , S , Granell , R , Curtin , J A , Holloway , J W , Fontanella , S , Arshad , S H , Murray , C S , Cullinan , P , Turner , S , Roberts , G , Simpson , A & Custovic , A 2024 , ' Identification

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Academic Journal

Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita with microcephaly

Subjects: Arthrogryposis/genetics; Carrier Proteins/genetics; Contracture

  • Source: Schnabel , F , Schuler , E , Al-Maawali , A , Chaurasia , A , Syrbe , S , Al-Kindi , A , Bhavani , G S , Shukla , A , Altmüller , J , Nürnberg , P , Banka , S , Girisha , K M , Li , Y , Wollnik , B

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Academic Journal

Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells.

Subjects: Animals; Antigen Presentation; Antigens/immunology

  • Source: Rodríguez-Silvestre , P , Laub , M , Krawczyk , PA , Davies , AK , Schessner , JP , Parveen , R , Tuck , BJ , McEwan , WA , Borner , GHH & Kozik , P 2023 , ' Perforin-2 is a pore-forming effector of

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Academic Journal

Ceg1 depletion reveals mechanisms governing degradation of non-capped RNAs in Saccharomyces cerevisiae

Subjects: Exonucleases/metabolism; RNA Caps/genetics; RNA

  • Source: Zanin , O , Eastham , M , Winczura , K , Ashe , M , Martinez-Nunez , R T , Hebenstreit , D & Grzechnik , P 2023 , ' Ceg1 depletion reveals mechanisms governing degradation of non-capped RNAs in

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Academic Journal

Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils

Subjects: Humans; Mice; Animals

  • Source: Huerga Encabo , H , Aramburu , I V , Garcia-Albornoz , M , Piganeau , M , Wood , H , Song , A , Ferrelli , A , Sharma , A , Minutti , C M , Domart , M-C , Papazoglou , D , Gurashi , K , Llorian Sopena

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Academic Journal

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.

Subjects: COVID-19/genetics; Critical Illness; Genetic Predisposition to Disease/genetics

  • Source: GenOMICC Investigators , SCOURGE Consortium , ISARICC Investigators , The 23andMe COVID-19 Team , et al. , & Hughes , G 2023 , ' GWAS and meta-analysis identifies 49 genetic variants underlying

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Academic Journal

Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results

Subjects: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins/genetics; DNA Damage

  • Source: Yap , T A , Fontana , E , Lee , E K , Spigel , D R , Højgaard , M , Lheureux , S , Mettu , N B , Carneiro , B A , Carter , L , Plummer , R , Cote , G M , Meric-Bernstam , F , O’Connell , J ,

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Academic Journal

A SAM-key domain required for enzymatic activity of the Fun30 nucleosome remodeler

Subjects: Adenosine Triphosphatases/genetics; DNA/metabolism; Nucleosomes/genetics

  • Source: Karl , L , Galanti , L , Bantele , S C S , Metzner , F , Šafarić , B , Rajappa , L , Foster , B , Pires , V B , Bansal , P , Chacin , E , Basquin , J , Duderstadt , K E , Kurat , C , Bartke , T ,

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