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Academic Journal

Caveolin mediates rapid glucocorticoid effects and couples glucocorticoid action to the antiproliferative program

Subjects: metabolism: 1-Phosphatidylinositol 3-Kinase; Animals; metabolism: Caveolin 1

  • Source: Matthews , L , Berry , A , Ohanian , V , Ohanian , J , Garside , H & Ray , D 2008 , ' Caveolin mediates rapid glucocorticoid effects and couples glucocorticoid action to the antiproliferative program

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Academic Journal

Thiazolidinediones are partial agonists for the glucocorticoid receptor

Subjects: drug effects: Cell Division; Cell Line; Tumor

  • Source: Matthews , L , Berry , A , Tersigni , M , D'Acquisto , F , Ianaro , A & Ray , D 2009 , ' Thiazolidinediones are partial agonists for the glucocorticoid receptor ' , Endocrinology , vol. 150 , no. 1 ,

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Academic Journal

Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1

Subjects: cell Hypoxia/drug effects; checkpoint Kinase 1; DNA Damage

  • Source: Pires , I M , Bencokova , Z , McGurk , C & Hammond , E M 2010 , ' Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1 ' , Cell cycle (Georgetown, Tex.) ,

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Academic Journal

Therapeutic potential of copper chelation with triethylenetetramine in managing diabetes mellitus and alzheimers disease

Subjects: Alzheimers disease; arteriosclerosis; Copper overload

  • Source: Cooper , G J S 2011 , ' Therapeutic potential of copper chelation with triethylenetetramine in managing diabetes mellitus and alzheimers disease ' , Drugs , vol. 71 , no. 10 , pp. 1281-1320 .

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Academic Journal

Scientific Lenses over Linked Data:An approach to support task specific views of the data. A vision.

  • Source: Brenninkmeijer , C , Evelo , C , Goble , C , Gray , A JG , Groth , P , Pettifer , S , Stevens , R , Williams , A J & Willighagen , E L 2012 , Scientific Lenses over Linked Data : An approach to

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Academic Journal

Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes

Subjects: Alleles; Animals; Anxiety/psychology

  • Source: O'Tuathaigh , C M P , Clarke , G , Walsh , J , Desbonnet , L , Petit , E , O'Leary , C , Tighe , O , Clarke , N , Karayiorgou , M , Gogos , J A , Dinan , T G , Cryan , J F & Waddington , J L 2012 , '

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Academic Journal

API-centric Linked Data integration:The Open PHACTS Discovery Platform case study

Subjects: Linked data; Data integration; Pharmacology

  • Source: Groth , P , Loizou , A , Gray , A J G , Goble , C , Harland , L & Pettifer , S 2014 , ' API-centric Linked Data integration : The Open PHACTS Discovery Platform case study ' , Journal of Web Semantics

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Academic Journal

Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery.

  • Source: Kell , D B & Goodacre , R 2014 , ' Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery. ' , Drug discovery today ,

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Academic Journal

Polymorphisms of serotonin neurotransmission and their effects on antipsychotic drug action

Subjects: 5-hydroxytryptamine; 5-HT receptors; antipsychotic drugs

  • Source: Tang , H , Reynolds , G P & McGowan , O 2014 , ' Polymorphisms of serotonin neurotransmission and their effects on antipsychotic drug action ' , Pharmacogenomics .

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Academic Journal

What would be the observable consequences if phospholipid bilayer diffusion of drugs into cells is negligible?

Subjects: drug transporters; lipoidal bilayer diffusion; physiologically based pharmacokinetic modelling

  • Source: Kell , D B 2015 , ' What would be the observable consequences if phospholipid bilayer diffusion of drugs into cells is negligible? ' , Trends in pharmacological sciences , vol. 36 , no. 1 .

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