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Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase

• Authors : Gravells, Polly; Grant, Emma; Smith, Kate M.

Subjects: BARD1; BRCA1; Breast cancer

• Source: Gravells , P , Grant , E , Smith , K M , James , D I & Bryant , H E 2017 , ' Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase ' , DNA Repair ,

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Rare EIF4A2 variants are associated with a neurodevelopmental disorder characterized by intellectual disability, hypotonia, and epilepsy

Subjects: DEAD-box protein; Drosophila; epilepsy

• Source: Genomics England Research Consortium 2023 , ' Rare EIF4A2 variants are associated with a neurodevelopmental disorder characterized by intellectual disability, hypotonia, and epilepsy ' , American

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Heterozygous loss-of-function SMC3 variants are associated with variable growth and developmental features

• Authors : Ansari, Morad; Faour, Kamli N W; Shimamura, Akiko

Subjects: CdLS3; Cornelia de Lange syndrome; LoF

• Source: Ansari , M , Faour , K N W , Shimamura , A , Grimes , G , Kao , E M , Denhoff , E R , Blatnik , A , Ben-Isvy , D , Wang , L , Helm , B M , Firth , H , Breman , A M , Bijlsma , E K , Iwata-Otsubo , A ,

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Heterozygous loss-of-function SMC3 variants are associated with variable and incompletely penetrant growth and developmental features.

• Authors : Ansari, Morad; Faour, Kamli N W; Shimamura, Akiko

• Source: Ansari , M , Faour , K N W , Shimamura , A , Grimes , G , Kao , E M , Denhoff , E R , Blatnik , A , Ben-Isvy , D , Wang , L , Helm , B M , Firth , H , Breman , A M , Bijlsma , E K , Iwata-Otsubo , A ,

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Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors

• Authors : Golder, Anya; Nelson, Louisa; Tighe, Anthony

Subjects: ResearchInstitutes_Networks_Beacons/mcrc; name=Manchester Cancer Research Centre

• Source: Golder , A , Nelson , L , Tighe , A , Barnes , B , Coulson-Gilmer , C , Morgan , R D , McGrail , J C & Taylor , S S 2022 , ' Multiple-low-dose therapy: effective killing of high-grade serous ovarian

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The impact of the COVID-19 pandemic on presentations to health services following self-harm: a systematic review

• Authors : Steeg, Sarah; John, Ann; Gunnell, David

• Source: Steeg , S , John , A , Gunnell , D , Kapur , N , Dekel , D , Schmidt , L , Knipe , D , Arensman , E , Hawton , K , Higgins , J PT , Eyles , E , Macleod-Hall , C , McGuiness , L A & Webb , R T 2022 , '

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Rare variants in KDR, encoding VEGF Receptor 2, are associated with tetralogy of Fallot.

• Authors : Škorić-Milosavljević, D; Lahrouchi, N; Bosada, FM

• Source: Škorić-Milosavljević , D , Lahrouchi , N , Bosada , FM , Dombrowsky , G , Williams , SG , Lesurf , R , Tjong , FVY , Walsh , R , El , B I , Breckpot , J , Audain , E , Bezzina , CR & Keavney , B

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Post-translational formation of hypusine in eIF5A:implications in human neurodevelopment

• Authors : Kar, Rajesh Kumar; Banka, Siddharth; Ziegler, Alban

Subjects: Deoxyhypusine hydroxylase; Deoxyhypusine synthase; Hypusine

• Source: Kar , R K , Banka , S , Ziegler , A & Chung , W K 2021 , ' Post-translational formation of hypusine in eIF5A : implications in human neurodevelopment ' , Amino acids .

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KRAS-mutant non-small cell lung cancer:Converging small molecules and immune checkpoint inhibition

• Authors : Adderley, Helen; Blackhall, Fiona H.; Lindsay, Colin R.

Subjects: ResearchInstitutes_Networks_Beacons/mcrc; name=Manchester Cancer Research Centre

• Source: Adderley , H , Blackhall , F H & Lindsay , C R 2019 , ' KRAS-mutant non-small cell lung cancer : Converging small molecules and immune checkpoint inhibition ' , EBioMedicine .

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Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas

• Authors : Liko, Dritan; Mitchell, Louise; Campbell, Kirsteen J.

Subjects: ResearchInstitutes_Networks_Beacons/mcrc; Manchester Cancer Research Centre

• Source: Liko , D , Mitchell , L , Campbell , K J , Ridgway , R A , Jones , C , Dudek , K , King , A , Bryson , S , Stevenson , D A , Blyth , K , Strathdee , D , Morton , J P , Bird , T G , Knight , J R P ,

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