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Academic Journal

Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway

Subjects: Humans; Immune Checkpoint Inhibitors/pharmacology; B7-H1 Antigen

  • Source: Hodson , D , Mistry , H , Guzzetti , S , Davies , M , Staniszewska , A , Farrington , P , Cadogan , E , Yates , J , Aarons , L & Ogungbenro , K 2023 , ' Mixed effects modeling of radiotherapy in

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Academic Journal

Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results

Subjects: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins/genetics; DNA Damage

  • Source: Yap , T A , Fontana , E , Lee , E K , Spigel , D R , Højgaard , M , Lheureux , S , Mettu , N B , Carneiro , B A , Carter , L , Plummer , R , Cote , G M , Meric-Bernstam , F , O’Connell , J ,

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Academic Journal

Oxidative DNA damage promotes vascular ageing associated with changes in extracellular matrix-regulating proteins

  • Source: Foote , K , Rienks , M , Schmidt , L , Theofilatos , K , Yasmin , S , Ozols , M , Eckersley , A , Shah , A , Figg , N , Finigan , A , O'Shaughnessy , K , Wilkinson , I B , Mayr , M & Bennett , M 2024

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Academic Journal

A non-coding RNA balancing act:miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer

Subjects: Cell Cycle; DNA Damage; Humans

  • Source: Fletcher , C E , Deng , L , Orafidiya , F , Yuan , W , Lorentzen , M P G S , Cyran , O W , Varela-Carver , A , Constantin , T A , Leach , D A , Dobbs , F M , Figueiredo , I , Gurel , B , Parkes , E ,

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Academic Journal

Identification and Validation of ERK5 as a DNA Damage Modulating Drug Target in Glioblastoma

Subjects: DNA damage; ERK5; Glioblastoma

  • Source: Carmell , N , Rominiyi , O , Myers , K N , McGarrity-Cottrell , C , Vanderlinden , A , Lad , N , Perroux-David , E , Sherif , A , Fernando , M , Finegan , K , Brown , S & Collis , S 2021 , '

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Academic Journal

PON1 increases cellular DNA damage by lactone substrates

Subjects: PON1; DNA damage; Lactones

  • Source: Shangula , S , Noori , M , Ahmad , I , Margison , G P , Liu , Y , Siahmansur , T , Soran , H & Povey , A C 2019 , ' PON1 increases cellular DNA

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Academic Journal

Effects of Differing Underlying Assumptions in In Silico Models on Predictions of DNA Damage and Repair

  • Source: Warmenhoven , J W , Henthorn , N T , Mcnamara , A L , Ingram , S P , Merchant , M J , Kirkby , K J , Schuemann , J , Paganetti , H , Prise , K M & Mcmahon , S J 2023 , ' Effects of Differing

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Academic Journal

Fractional sunburn threshold UVR doses generate equivalent vitamin D and DNA damage in skin types I-VI, but with epidermal DNA damage gradient correlated to skin darkness

Subjects: Ultraviolet radiation; vitamin D; DNA damage

  • Source: Shih , B B , Farrar , M D , Cooke , M S , Osman , J , Langton , A K , Kift , R , Webb , A R , Berry , J L , Watson , R E B , Vail , A , Gruijl , F R D & Rhodes , L E 2018 , ' Fractional sunburn

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