نتائج البحث

Cell-free and extrachromosomal DNA profiling of small cell lung cancer

• Authors : Behrouzi, Roya; Clipson, Alexandra; Simpson, Kathryn l.

Subjects: small cell lung cancer; liquid biopsy; cell-free DNA

• Source: Behrouzi , R , Clipson , A , Simpson , K L , Blackhall , F , Rothwell , D G , Dive , C & Mouliere , F 2024 , ' Cell-free and extrachromosomal DNA profiling of small cell

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Small molecule inhibition of CBX4/7 hypersensitises homologous recombination-impaired cancer to radiation by compromising CtIP-mediated DNA end resection

• Authors : Osborne, Hugh; Foster, Benjamin; Al-Hazmi, Hazim

Subjects: cancer; DNA repair; DNA end resection

• Source: Osborne , H , Foster , B , Al-Hazmi , H , Meyer , S , Larrosa , I & Schmidt , C 2024 , ' Small molecule inhibition of CBX4/7 hypersensitises homologous recombination-impaired cancer to radiation by

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DNA damage in prepared semen is negatively associated with semen quality and fertilisation rate in assisted reproduction technology (ART) treatment

• Authors : Altakroni, Bashar; Hunter, Helen; Horne, Greg

Subjects: DNA damage; DNA integrity; Comet assay

• Source: Altakroni , B , Hunter , H , Horne , G , Brison , D R & Povey , A C 2024 , ' DNA damage in prepared semen is negatively associated with semen quality and fertilisation

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Discovery of DNA methylation signature in the peripheral blood of individuals with history of antenatal exposure to valproic acid

• Authors : Haghshenas, Sadegheh; Putoux, Audrey; Reilly, Jack

Subjects: DNA methylation; Epigenetics; Episignature

• Source: Haghshenas , S , Putoux , A , Reilly , J , Levy , M A , Relator , R , Ghosh , S , Kerkhof , J , McConkey , H , Edery , P , Lesca , G , Besson , A , Coubes , C , Willems , M , Ruiz-Pallares , N ,

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Menke-Hennekam syndrome; delineation of domain-specific subtypes with distinct clinical and DNA methylation profiles

Subjects: CREB-binding protein; DNA methylation; E1A-associated protein p300

• Source: MKHK Research Consortium 2024 , ' Menke-Hennekam syndrome; delineation of domain-specific subtypes with distinct clinical and DNA methylation profiles ' , Human Genetics

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Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome.

• Authors : Green, Jack; El-Sharkawy, Lina; Roth, Stefan

Subjects: AIM2; cGAS-STING; DNA-sensing

• Source: Green , J , El-Sharkawy , L , Roth , S , Zhu , J , Cao , J , Leach , A , Liesz , A , Freeman , S & Brough , D 2024 , ' Discovery of an inhibitor of DNA-driven

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The Bracken Fern Carcinogen, Ptaquiloside, Forms a Guanine O 6 -Adduct in DNA

• Authors : Keskin, Fourat; Noone, Hannah; Dickman, Mark J.

Subjects: Bracken fern; ptaquiloside; carcinogenicity

• Source: Keskin , F , Noone , H , Dickman , M J , Allen , E , Mulcrone , W D , Rasmussen , L H , Hansen , H C B , O'Connor , P J , Povey , A C , Margison , G P & Williams , D M 2025 , ' The Bracken Fern

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DNA-binding affinity and specificity determine the phenotypic diversity in BCL11B-related disorders

Subjects: BCL11B; C2H2-type zinc finger protein; genotype-phenotype correlation

• Source: Undiagnosed Diseases Network 2025 , ' DNA-binding affinity and specificity determine the phenotypic diversity in BCL11B-related disorders ' , American Journal of Human

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DNA methylation analysis in patients with neurodevelopmental disorders improves variant interpretation and reveals complexity

• Authors : Trajkova, Slavica; Kerkhof, Jennifer; Sebastiano, Matteo Rossi

Subjects: ARID1A; ARID1B; BAFopathy

• Source: Trajkova , S , Kerkhof , J , Sebastiano , M R , Pavinato , L , Ferrero , E , Giovenino , C , Carli , D , Di Gregorio , E , Marinoni , R , Mandrile , G , Palermo , F , Carestiato , S , Cardaropoli , S

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Mass spectrometric analysis of the active site tryptic peptide of recombinant O 6 -methylguanine-DNA methyltransferase following incubation with human colorectal DNA reveals the presence of an O 6 -alkylguanine adductome.

• Authors : Abdelhady, Rasha; Senthong, Pattama; Eyers, Claire E.

Subjects: O6 -alkylguanine; DNA adducts; MGMT

• Source: Abdelhady , R , Senthong , P , Eyers , C E , Reamtong , O , Cowley , E , Cannizzaro , L , Stimpson , J , Cain , K , Wilkinson , O J , Williams , N H , Barran , P , Margison , G P , Williams , D &

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