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Academic Journal

USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF

Subjects: Humans; Vascular Endothelial Growth Factor A; Immune Checkpoint Inhibitors/pharmacology

  • Source: Jurisic , A , Sung , P-J , Wappett , M , Daubriac , J , Lobb , I T , Kung , W-W , Crawford , N , Page , N , Cassidy , E , Feutren-Burton , S , Rountree , J S S , Helm , M D , O'Dowd , C R , Kennedy ,

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Academic Journal

The E3 ubiquitin ligase Itch regulates death receptor and cholesterol trafficking to affect TRAIL-mediated apoptosis

Subjects: Cisplatin; Cholesterol; Cytochromes c

  • Source: Holloway , J , Seeley , A , Cobbe , N , Turkington , R C , Longley , D B & Evergren , E 2024 , ' The E3 ubiquitin ligase Itch regulates death receptor and cholesterol trafficking to affect

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Academic Journal

Effects of PROtein enriched MEDiterranean Diet and EXercise on nutritional status and cognition in adults at risk of undernutrition and cognitive decline: the PROMED-EX Randomised Controlled Trial

Subjects: Humans; Middle Aged; Aged

  • Source: Ward , N A , Reid-McCann , R , Brennan , L , Cardwell , C R , de Groot , CPGM , Maggi , S , McCaffrey , N , McGuinness , B , McKinley , M C , Noale , M , O'Neill , R F , Prinelli , F , Sergi , G ,

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Academic Journal

A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection

Subjects: Cullin Proteins - metabolism; Immunity; Innate

  • Source: Sá-Pessoa , J , López-Montesino , S , Przybyszewska , K , Rodríguez-Escudero , I , Marshall , H , Ova , A , Schroeder , G N , Barabas , P , Molina , M , Curtis , T , Cid , V J & Bengoechea , J A

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Academic Journal

Akkermansia muciniphila and its membrane protein ameliorates intestinal inflammatory stress and promotes epithelial wound healing via CREBH and miR-143/145

Subjects: Humans; Animals; Mice

  • Source: Wade , H , Pan , K , Duan , Q , Kaluzny , S , Pandey , E , Fatumoju , L , Saraswathi , V , Wu , R , Harris , E N & Su , Q 2023 , ' Akkermansia muciniphila and its membrane protein ameliorates

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Academic Journal

Oxidation modulates LINGO2-induced inactivation of large conductance, Ca2 + -activated potassium channels

Subjects: LINGO subunits; Potassium channel; biophysics

  • Source: Dudem , S , Boon , P X , Mullins , N , McClafferty , H , Shipston , M J , Wilkinson , R D A , Lobb , I , Sergeant , G P , Thornbury , K D , Tikhonova , I G & Hollywood , M A 2023 , ' Oxidation

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Academic Journal

Gα q signalling from endosomes: a new conundrum

Subjects: endocytosis; phosphoinositides; membrane lipids

  • Source: Daly , C & Plouffe , B 2023 , ' Gα q signalling from endosomes: a new conundrum ' , British Journal of Pharmacology . https://doi.org/10.1111/bph.16248

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Academic Journal

The effect of animal versus plant protein on muscle mass, muscle strength, physical performance and sarcopenia in adults: protocol for a systematic review

Subjects: Aged; Animal protein; Animals

  • Source: Reid-McCann , R J , Brennan , S F , McKinley , M C & McEvoy , C T 2022 , ' The effect of animal versus plant protein on muscle mass, muscle strength, physical performance and sarcopenia in adults:

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Academic Journal

Emerging Roles of TRIM Family Proteins in Gliomas Pathogenesis

Subjects: brain tumors; glioblastoma; gliomagenesis

  • Source: Giannopoulou , A I , Xanthopoulos , C , Piperi , C & Kostareli , E 2022 , ' Emerging Roles of TRIM Family Proteins in Gliomas Pathogenesis ' , Cancers , vol. 14 , no. 18

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