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Identification of Src as a therapeutic target in oesophageal adenocarcinoma through functional genomic and high-throughput drug screening approaches

• Authors : McCabe, Niamh H.; Stevenson, Leanne; Scanlon, Enya

Subjects: oesophageal cancer; chemotherapy; drug resistance

• Source: McCabe , N H , Stevenson , L , Scanlon , E , Douglas , R , Kennedy , S , Keminer , O , Windshügel , B , Zisterer , D , Kennedy , R D , Blayney , J K & Turkington , R C 2022 , ' Identification of Src

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Abstract 2999: Identification of Src's role in governing chemotherapy resistance in oesophageal adenocarcinoma through functional genomic and high-throughput drug screening approaches

• Authors : McCabe, Niamh

• Source: McCabe , N 2020 , ' Abstract 2999: Identification of Src's role in governing chemotherapy resistance in oesophageal adenocarcinoma through functional genomic and high-throughput

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Exploring the active core of a novel antimicrobial peptide, palustrin-2LTb, from the Kuatun frog, Hylarana latouchii, using a bioinformatics-directed approach

• Authors : Zou, Wanchen; Zhang, Yingqi; Zhou, Mei

Subjects: Antimicrobial peptides; Multi-drug resistance; In silico design

• Source: Zou , W , Zhang , Y , Zhou , M , Chen , X , Ma , C , Wang , T , Jiang , Y , Chen , T , Shaw , C & Wang , L 2022 , ' Exploring the active core of a novel antimicrobial peptide, palustrin-2LTb, from the

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Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids

• Authors : Naderi-Meshkin, Hojjat; Setyaningsih, Wiwit A Wahyu; Yacoub, Andrew

Subjects: Induced Pluripotent Stem Cells; Cardiovascular Diseases; Diabetic Vasculopathy

• Source: Naderi-Meshkin , H , Setyaningsih , W A W , Yacoub , A , Carney , G , Cornelius , V A , Nelson , C-A , Kelaini , S , Donaghy , C , Dunne , P D , Amirkhah , R , Zampetaki , A , Zeng , L , Stitt , A W ,

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Spheroids in cancer research: recent advances and opportunities

• Authors : Arora, Sanchit; Singh, Somay; Mittal, Anuj

Subjects: Spheroids; cancer research; advances

• Source: Arora , S , Singh , S , Mittal , A , Desai , N , Khatri , D K , Gugulothu , D , Lather , V , Pandita , D & Vora , L K 2024 , ' Spheroids in cancer research: recent advances and opportunities ' ,

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Ruthenium drug BOLD-100 regulates BRAFMT colorectal cancer cell apoptosis through AhR/ROS/ATR signaling axis modulation

• Authors : Griffin, Daryl; Carson, Robbie; Moss, Debbie

Subjects: ruthenium drug; BOLD-100; BRAFMT

• Source: Griffin , D , Carson , R , Moss , D , Sessler , T , Lavin , D , Tiwari , V , Karelia , S , Kennedy , R , Savage , K I , McDade , S , Carie , A , Pankovich , J , Bazett , M & Van Schaeybroeck , S 2024

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Are the Apo Proteins Suitable for the Rational Discovery of Allosteric Drugs

• Authors : An, Xiaoli; Lu, Shaoyong; Song, Kun

• Source: An , X , Lu , S , Song , K , Shen , Q , Huang , M , Yao , X , Liu , H & Zhang , J 2018 , ' Are the Apo Proteins Suitable for the Rational Discovery of Allosteric Drugs ' , Journal of Chemical

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Bcl-xL is a key mediator of apoptosis following KRAS G12C inhibition in KRAS G12C -mutant colorectal cancer

• Authors : Khawaja, Hajrah; Briggs, Rebecca; Latimer, Cheryl H.

Subjects: Cancer Research; Oncology; /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being

• Source: Khawaja , H , Briggs , R , Latimer , C H , Rassel , M , Griffin , D , Hanson , L , Bardelli , A , Di Nicolantonio , F , McDade , S S , Scott , C J , Lambe , S , Maurya , M , Lindner , A U , Prehn , J

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Combination therapies targeting apoptosis in paediatric AML: understanding the molecular mechanisms of AML treatments using phosphoproteomics

• Authors : Ali, Ahlam A.; Cairns, Lauren V.; Clarke, Kathryn M.

Subjects: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being; name=SDG 3 - Good Health and Well-being

• Source: Ali , A A , Cairns , L V , Clarke , K M , Blayney , J K , Lappin , K M & Mills , K I 2023 , ' Combination therapies targeting apoptosis in paediatric AML: understanding the molecular mechanisms of AML

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Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists

• Authors : Grinkevich, Vera; Wappett, Mark; Crawford, Nyree

Subjects: Cancer Research; Oncology

• Source: Grinkevich , V , Wappett , M , Crawford , N , Price , S , Lees , A , McCann , C , McAllister , K A , Prehn , J H , Young , J , Bateson , J H , Gallagher , L , Michaut , M , Iyer , V , Chatzipli , A ,

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