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An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma

• Authors : Baxter, M. A.; Spender, L. C.; Cairns, D.

Subjects: Humans; immune checkpoint inhibitors; Immune Checkpoint Inhibitors - therapeutic use - pharmacology

• Source: Baxter, M A, Spender, L C, Cairns, D, Walsh, S, Oparka, R, Porter, R J, Bray, S, Skinner, G, King, S, Turbitt, J, Collinson, D, Miedzybrodzka, Z H, Jellema, G, Logan, G, Kennedy, R D, Turkington, R C,

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Monte Carlo damage models of different complexity levels predict similar trends in radiation induced DNA damage

• Authors : Thompson, Shannon J; Prise, Kevin M; McMahon, Stephen J

Subjects: Monte Carlo; radiation biology; DNA damage

• Source: Thompson, S J, Prise, K M & McMahon, S J 2024, 'Monte Carlo damage models of different complexity levels predict similar trends in radiation induced

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Integrated multimodal analyses of DNA damage response and immune markers as predictors of response in metastatic triple-negative breast cancer in the TNT trial (NCT00532727)

• Authors : Tovey, Holly; Sipos, Orsolya; Parker, Joel S

Subjects: Humans; Carboplatin; BRCA1 Protein/genetics

• Source: Tovey, H, Sipos, O, Parker, J S, Hoadley, K A, Quist, J, Kernaghan, S, Kilburn, L, Salgado, R, Loi, S, Kennedy, R D, Roxanis, I, Gazinska, P, Pinder, S E, Bliss, J, Perou, C M, Haider, S, Grigoriadis,

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Synergistic activity of DNA damage response inhibitors in combination with radium-223 in prostate cancer

• Authors : Dunne, Victoria L.; Wright, Timothy C.; Liberal, Francisco D. C. Guerra

Subjects: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being; name=SDG 3 - Good Health and Well-being

• Source: Dunne, V L, Wright, T C, Liberal, F D C G, O'Sullivan, J M & Prise, K M 2024, 'Synergistic activity of DNA damage response inhibitors in

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A DNA-damage immune response assay combined with PET biomarkers predicts response to neo-adjuvant chemotherapy and survival in oesophageal adenocarcinoma

• Authors : Foley, Kieran G; Lavery, Anita; Napier, Eoin

Subjects: Adenocarcinoma/diagnostic imaging; Adult; Aged

• Source: Foley, K G, Lavery, A, Napier, E, Campbell, D, Eatock, M M, Kennedy, R D, Bradley, K M & Turkington, R C 2021, 'A DNA-damage immune

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Oxygen enhancement ratios of cancer cells after exposure to intensity modulated x-ray fields: DNA damage and cell survival

• Authors : Matsuya, Yusuke; McMahon, Stephen J.; Butterworth, Karl T.

Subjects: Cell survival; DNA damage; Intensity modulated radiation fields

• Source: Matsuya, Y, McMahon, S J, Butterworth, K T, Naijo, S, Nara, I, Yachi, Y, Saga, R, Ishikawa, M, Sato, T, Date, H & Prise, K M 2021, 'Oxygen enhancement ratios of cancer cells after exposure to

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DNA damage in testicular germ cells and spermatozoa. When and how is it induced? How should we measure it? What does it mean?

• Authors : Aitken, Robert John; Lewis, Sheena E.M.

Subjects: Urology; Endocrinology; Reproductive Medicine

• Source: Aitken, R J & Lewis, S E M 2023, 'DNA damage in testicular germ cells and spermatozoa. When and how is it induced? How should we measure

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Dual prognostic classification of triple-negative breast cancer by DNA damage immune response and homologous recombination deficiency

• Authors : Stecklein, Shane R.; Barlow, William; Pusztai, Lajos

Subjects: Cancer Research; Oncology; /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being

• Source: Stecklein, S R, Barlow, W, Pusztai, L, Timms, K, Kennedy, R, Logan, G E, Seitz, R, Badve, S, Gökmen-Polar, Y, Porter, P, Linden, H, Tripathy, D, Hortobagyi, G N, Godwin, A K, Thompson, A, Hayes, D F

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Evaluating iodine-125 DNA damage benchmarks of Monte Carlo DNA damage models

• Authors : Thompson, Shannon J.; Rooney, Aoife; Prise, Kevin M.

• Source: Thompson, S J, Rooney, A, Prise, K M & McMahon, S J 2022, 'Evaluating iodine-125 DNA damage benchmarks of Monte Carlo

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Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma

• Authors : Turkington, Richard; Knight, Laura; Blayney, Jaine

Subjects: Adenocarcinoma/immunology; Aged; Antineoplastic Agents/therapeutic use

• Source: Turkington, R, Knight, L, Blayney, J, Secrier, M, Douglas, R, Parkes, E, Sutton, E, Stevenson, L, McManus, D, Halliday, S, McCavigan, A, Logan, G, Walker, S, Steele, C, Perner, J, Bornscein, J,

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