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Academic Journal

Significance of NPM1 Gene Mutations in AML

Subjects: AML; DNMT3A; FLT3

  • Source: Hindley , A , Catherwood , M A , McMullin , M F & Mills , K I 2021 , ' Significance of NPM1 Gene Mutations in AML ' , International Journal of Molecular Sciences , vol.

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Academic Journal

FLT3 inhibitors as MRD-guided salvage treatment for molecular failure in FLT3 mutated AML

  • Source: Othman , J , Potter , N , Mokretar , K , Taussig , D , Khan , A , Krishnamurthy , P , Latif , A-L , Cahalin , P , Aries , J , Amer , M , Belsham , E , Conneally , E , Craddock , C , Culligan , D ,

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Academic Journal

Low-dose salinomycin induces anti-leukemic responses in AML and MLL

Subjects: drug repurposing; salinomycin; anti-leukemia

  • Source: Roulston , G D R , Burt , C L , Kettyle , L M J , Matchett , K B , Keenan , H L , Mulgrew , N M , Ramsey , J M , Dougan , C , McKiernan , J , Grishagin , I V , Mills , K I & Thompson , A 2016 , '

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Academic Journal

S130: NPM1 mutated AML: impact of co-mutational patterns - results of the European Harmony Alliance

Subjects: Hematology

  • Source: Hernández-Sánchez , A , Villaverde-Ramiro , Á , Martínez Elicegui , J , González , T , Benner , A , Sträng , E , Castellani , G , Heckman , C A , Versluis , J , Abáigar , M , Sobas , M ,

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Academic Journal

P463: Re-purposing of gene signatures in AML uncovers novel energetics-associated molecular subtypes

Subjects: Hematology

  • Source: Strain , P , Scanlon , E E , Jellema , G , Kennedy , R D , Mills , K I & Blayney , J K 2022 , ' P463: Re-purposing of gene signatures in AML uncovers novel

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Academic Journal

Chronic loss of STAG2 leads to altered chromatin structure contributiong to de-regulated transcription in AML

Subjects: Acute myeloid leukaemia; ChIP-seq; Cohesion

  • Source: Smith , J , Lappin , K , Craig , S , Liberante , F , McDade , S , Thompson , A , Mills , K & Savage , K 2020 , ' Chronic loss of STAG2 leads to altered chromatin structure contributiong to

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Academic Journal

Bithionol eliminates acute myeloid leukaemia stem-like cells by suppressing NF-κB signalling and inducing oxidative stress, leading to apoptosis and ferroptosis

Subjects: Acute myeloid leukaemia; AML; bone marrow

  • Source: Dias , I R S B , Costa , R G A , Rodrigues , A C B D C , Silva , S L R , Oliveira , M D S , Soares , M B P , Dias , R B , Valverde , L F , Gurgel Rocha , C A , Cairns , L V , Mills , K I & Bezerra , D

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Academic Journal

The Molecular Landscape of AML

  • Source: Lappin , K , Clarke , K & Mills , K 2020 , ' The Molecular Landscape of AML ' , HemaSphere , vol. 4 , no. S2 , pp. 112-114 . https://doi.org/10.1097/HS9.0000000000000444

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Academic Journal

DEK oncogene expression during normal hematopoiesis and in Acute Myeloid Leukemia (AML)

  • Source: Logan , G E , Mor-Vaknin , N , Braunschweig , T , Jost , E , Schmidt , P V , Markovitz , D M , Mills , K I , Kappes , F & Percy , M J 2015 , ' DEK oncogene expression during normal hematopoiesis and

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