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Roles of Coagulation Proteases and PARs (Protease-Activated Receptors) in Mouse Models of Inflammatory Diseases

• Authors : Posma, Jens J; Grover, Steven P; Hisada, Yohei

Subjects: DIET-INDUCED OBESITY; DIRECT THROMBIN INHIBITOR; FACTOR GENE-EXPRESSION

• Source: Posma , J J , Grover , S P , Hisada , Y , Owens , A P , Antoniak , S , Spronk , H M & Mackman , N 2019 , ' Roles of Coagulation Proteases and PARs (Protease-Activated

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Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation

• Authors : Vangansewinkel, Tim; Lemmens, Stefanie; Tiane, Assia

Subjects: astrogliosis; demyelination; functional recovery

• Source: Vangansewinkel , T , Lemmens , S , Tiane , A , Geurts , N , Dooley , D , Vanmierlo , T , Pejler , G & Hendrix , S 2023 , ' Therapeutic administration of mouse mast cell protease 6 improves functional

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Disarray at the membrane:regulation of vascular inflammation by cholesterol and proteases

• Authors : Theodorou, Kostantinos

• Source: Theodorou , K 2018 , ' Disarray at the membrane : regulation of vascular inflammation by cholesterol and proteases ' , Maastricht University , Maastricht .

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Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

• Authors : Yadati, Tulasi; Houben, Tom; Bitorina, Albert

Subjects: NASH; lysosomal enzymes; lipoprotein metabolism

• Source: Yadati , T , Houben , T , Bitorina , A , Oligschlaeger , Y , Gijbels , M J , Mohren , R , Lütjohann , D , Khurana , P , Goyal , S , Kulkarni , A , Theys , J , Cillero-Pastor , B & Shiri-Sverdlov , R

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Programmed 'disarming' of the neutrophil proteome reduces the magnitude of inflammation

• Authors : Adrover, Jose M.; Aroca-Crevillen, Alejandra; Crainiciuc, Georgiana

Subjects: CIRCADIAN VARIATION; SECRETORY VESICLES; SERINE PROTEASES

• Source: Adrover , J M , Aroca-Crevillen , A , Crainiciuc , G , Ostos , F , Rojas-Vega , Y , Rubio-Ponce , A , Cilloniz , C , Bonzon-Kulichenko , E , Calvo , E , Rico , D , Moro , M A , Weber , C , Lizasoain ,

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Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague-Dawley Rats

• Authors : Khurana, Princy; Yadati, Tulasi; Goyal, Sandeep

Subjects: NAFLD; lysosomal enzyme; extracellular cathepsin D

• Source: Khurana , P , Yadati , T , Goyal , S , Dolas , A , Houben , T , Oligschlaeger , Y , Agarwal , A K , Kulkarni , A & Shiri-Sverdlov , R 2019 , ' Inhibiting Extracellular Cathepsin D Reduces Hepatic

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Mast cell chymase inhibition reduces atherosclerotic plaque progression and improves plaque stability in ApoE(-/-) mice

• Authors : Bot, Ilze; Bot, Martine; van Heiningen, Sandra H.

Subjects: Atherosclerosis; Mast cells; Proteases

• Source: Bot , I , Bot , M , van Heiningen , S H , van Santbrink , P J , Lankhuizen , I M , Hartman , P , Gruener , S , Hilpert , H , van Berkel , T J C , Fingerle , J & Biessen , E A L 2011 , ' Mast cell

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Urine peptidome in combination with transcriptomics analysis highlights MMP7, MMP14 and PCSK5 for further investigation in chronic kidney disease

• Authors : Petra, Eleni; Siwy, Justyna; Vlahou, Antonia

Subjects: Aged; Biomarkers; Body Fluids/metabolism

• Source: Petra , E , Siwy , J , Vlahou , A & Jankowski , J 2022 , ' Urine peptidome in combination with transcriptomics analysis highlights MMP7, MMP14 and PCSK5 for further investigation in chronic kidney

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Platelet Membrane Receptor Proteolysis: Implications for Platelet Function

• Authors : Wu, J.Y.; Heemskerk, J.W.M.; Baaten, C.C.F.M.J.

Subjects: adam; calpain; calpain cleavage

• Source: Wu , J Y , Heemskerk , J W M & Baaten , C C F M J 2021 , ' Platelet Membrane Receptor Proteolysis: Implications for Platelet Function ' , Frontiers in cardiovascular medicine , vol. 7 , 608391 .

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Urine peptidome analysis in cardiorenal syndrome reflects molecular processes

• Authors : Petra, Eleni; He, Tianlin; Lygirou, Vasiliki

Subjects: CHRONIC KIDNEY-DISEASE; HEART-FAILURE; MYOCARDIAL-INFARCTION

• Source: Petra , E , He , T , Lygirou , V , Latosinska , A , Mischak , H , Vlahou , A & Jankowski , J 2021 , ' Urine peptidome analysis in cardiorenal syndrome reflects molecular processes ' , Scientific

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