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Academic Journal

Low mitochondrial DNA copy number in buffy coat DNA of primary open-angle glaucoma patients

Subjects: Trabecular meshwork; Oxidative stress; Optic neuropathy

  • Source: Vallbona-Garcia , A , Hamers , I H J , van Tienen , F H J , Ochoteco-Asensio , J , Berendschot , T T J M , de Coo , I F M , Benedikter , B J , Webers , C A B , Smeets , H J M & Gorgels , T G M F 2023

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Academic Journal

Mitochondrial DNA D-loop variants correlate with a primary open-angle glaucoma subgroup

Subjects: D-loop (control region); glaucoma; mitochondria

  • Source: Vallbona-Garcia , A , Lindsey , P J , Kamps , R , Stassen , A P M , Nguyen , N , van Tienen , F H J , Hamers , I H J , Hardij , R , van Gisbergen , M W , Benedikter , B J , de Coo , I F M , Webers , C

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Academic Journal

The Cord Blood Insulin and Mitochondrial DNA Content Related Methylome

Subjects: insulin; mitochondrial DNA content; epigenome-wide methylation

  • Source: Reimann , B , Janssen , B G , Alfano , R , Ghantous , A , Espin-Perez , A , de Kok , T M , Saenen , N D , Cox , B , Robinson , O , Chadeau-Hyam , M , Penders , J , Herceg , Z , Vineis , P , Nawrot , T

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Academic Journal

PGD for the m.14487 T>C mitochondrial DNA mutation resulted in the birth of a healthy boy

Subjects: PGD; mitochondrial DNA (mtDNA) mutation; T14487C

  • Source: Sallevelt , S C E H , Dreesen , J C F M , Druesedau , M , Hellebrekers , D M E I , Paulussen , A D C , Coonen , E , Van Golde , R J T , Geraedts , J P M , Gianaroli , L , Magli , M C , Zeviani , M ,

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Academic Journal

Phenotypic spectrum and clinical course of single large-scale mitochondrial DNA deletion disease in the paediatric population: a multicentre study

Subjects: congenital; hereditary; and neonatal diseases and abnormalities

  • Source: Bjorkman , K , Vissing , J , Ostergaard , E , Bindoff , L A , de Coo , I F M , Engvall , M , Hikmat , O , Isohanni , P , Kollberg , G , Lindberg , C , Majamaa , K , Naess , K , Uusimaa , J , Tulinius

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Academic Journal

Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase

Subjects: complex V; DNA replication; mitochondrial biogenesis

  • Source: Fukuoh , A , Cannino , G , Gerards , M , Buckley , S , Kazancioglu , S , Scialo , F , Lihavainen , E , Ribeiro , A , Dufour , E & Jacobs , H T 2014 , ' Screen for

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Academic Journal

PGD and heteroplasmic mitochondrial DNA point mutations: a systematic review estimating the chance of healthy offspring

Subjects: PGD; mitochondrial DNA mutations; heteroplasmy

  • Source: Hellebrekers , D M E I , Wolfe , R , Hendrickx , A T M , de Coo , I F M , de Die , C E , Geraedts , J P M , Chinnery , P F & Smeets , H J M 2012 , ' PGD and heteroplasmic

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Academic Journal

RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA

Subjects: mitochondria; DNA replication; RNA

  • Source: Gonzalez de Cozar , J M , Gerards , M , Teeri , E , George , J , Dufour , E , Jacobs , H T & Joers , P 2019 , ' RNase H1 promotes replication fork progression through oppositely transcribed regions of

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Academic Journal

Nuclear transfer to prevent mitochondrial DNA disorders: revisiting the debate on reproductive cloning

Subjects: ethics; mitochondrial DNA disorders; nuclear transfer

  • Source: Bredenoord , A L , Dondorp , W , Pennings , G & De Wert , G 2011 , ' Nuclear transfer to prevent mitochondrial DNA disorders: revisiting

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