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Polymeric Nanoparticles Enable mRNA Transfection and Its Translation in Intervertebral Disc and Human Joint Cells, Except for M1 Macrophages

• Authors : Muenzebrock, Katrin Agnes; Ho, Fiona Y W; Pontes, Adriano P

Subjects: chronic lower back pain; mRNA delivery; nanomedicine

• Source: Muenzebrock , K A , Ho , F Y W , Pontes , A P , Jorquera-Cordero , C , Utomo , L , Garcia , J P , Willems , P C , Welting , T J M , Rip , J & Creemers , L B 2024 , ' Polymeric Nanoparticles Enable

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A Membranome-Centered Approach Defines Novel Biomarkers for Cellular Subtypes in the Intervertebral Disc

• Authors : van den Akker, Guus G. H.; Eijssen, Lars M. T.; Richardson, Stephen M.

Subjects: intervertebral disc; cell lines; nucleus pulposus

• Source: van den Akker , G G H , Eijssen , L M T , Richardson , S M , van Rhijn , L W , Hoyland , J A , Welting , T J M & Voncken , J W 2020 , ' A Membranome-Centered Approach Defines Novel Biomarkers for

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Biomechanical evaluation of a novel biomimetic artificial intervertebral disc in canine cervical cadaveric spines

• Authors : Jacobs, C.A.M.; Doodkorte, R.J.P.; Kamali, S.A.

Subjects: biomechanical; biomimetic artificial disc; cervical spine

• Source: Jacobs , C A M , Doodkorte , R J P , Kamali , S A , Abdelgawad , A M , Ghazanfari , S , Jockenhoevel , S , Arts , J J C , Tryfonidou , M A , Meij , B P & Ito , K 2023 , ' Biomechanical evaluation of a

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Mechanics and biology in intervertebral disc degeneration: a vicious circle

• Authors : Vergroesen, P. -P. A.; Kingma, I.; Emanuel, K. S.

Subjects: Intervertebral disc; Intervertebral disc degeneration; Pathology

• Source: Vergroesen , P -P A , Kingma , I , Emanuel , K S , Hoogendoorn , R J W , Welting , T J , van Royen , B J , van Dieen , J H & Smit , T H 2015 , ' Mechanics and biology in

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Drug delivery in intervertebral disc degeneration and osteoarthritis:Selecting the optimal platform for the delivery of disease-modifying agents

• Authors : Colella, Fabio; Garcia, Joao Pedro; Sorbona, Marco

Subjects: PLATELET-RICH PLASMA; LOW-BACK-PAIN; FIBRIN/HYALURONIC ACID HYDROGEL

• Source: Colella , F , Garcia , J P , Sorbona , M , Lolli , A , Antunes , B , D'Atri , D , Barre , F P Y , Oieni , J , Vainieri , M L , Zerrillo , L , Capar , S , Haeckel , S , Cai , Y & Creemers , L B 2020 ,

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Prognostic factors in the progression of intervertebral disc degeneration:Which patient should be targeted with regenerative therapies?

• Authors : Rustenburg, Christine M E; Faraj, Sayf S A; Ket, Johannes C F

Subjects: 5-YEAR FOLLOW-UP; ASSOCIATION; BONE-MARROW

• Source: Rustenburg , C M E , Faraj , S S A , Ket , J C F , Emanuel , K S & Smit , T H 2019 , ' Prognostic factors in the progression of intervertebral

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Osteoarthritis and intervertebral disc degeneration:Quite different, quite similar

• Authors : Rustenburg, Christine M E; Emanuel, Kaj S; Peeters, Mirte

• Source: Rustenburg , C M E , Emanuel , K S , Peeters , M , Lems , W F , Vergroesen , P-P A & Smit , T H 2018 , ' Osteoarthritis and intervertebral

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Biomolecular therapies for chronic discogenic low back pain:A narrative review

• Authors : Rudnik-Jansen, Imke; Kodele, Sanda van Kruining; Creemers, Laura

Subjects: biologic therapies; degeneration; pain

• Source: Rudnik-Jansen , I , Kodele , S V K , Creemers , L & Joosten , B 2024 , ' Biomolecular therapies for chronic discogenic low back pain : A narrative review ' , JOR spine , vol. 7 , no. 3 , e1345 .

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Engineering Sensory Ganglion Multicellular System to Model Tissue Nerve Ingrowth

• Authors : Ma, Junxuan; Eglauf, Janick; Grad, Sibylle

Subjects: acoustic assembly; advanced in vitro models; alternatives to animal testing

• Source: Ma , J , Eglauf , J , Grad , S , Alini , M & Serra , T 2024 , ' Engineering Sensory Ganglion Multicellular System to Model Tissue Nerve Ingrowth ' , Advanced Science , vol. 11 , no. 11 , 2308478 .

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Drug retention after intradiscal administration

• Authors : Rudnik-Jansen, Imke; Du, Jie; Karssemakers-Degen, Nina

Subjects: Drug retention; peptide; small molecule

• Source: Rudnik-Jansen , I , Du , J , Karssemakers-Degen , N , Tellegen , A R , Wadhwani , P , Zuncheddu , D , Meij , B P , Thies , J , Emans , P , Oner , F C , Mihov , G , Garcia , J P , Ulrich , A S , Grad ,

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