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  • 1-10 ل  43 نتائج ل ""Catalytic Domain""
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Academic Journal

DNA topoisomerase 1 represses HIV-1 promoter activity through its interaction with a guanine quadruplex present in the LTR sequence

Subjects: DNA topoisomerases; Guanine quadruplex; HIV-1 LTR promoter

  • Source: ISSN: 1742-4690 ; Retrovirology ; https://hal.science/hal-04136961 ; Retrovirology, 2023, 20 (1), pp.10. ⟨10.1186/s12977-023-00625-8⟩.

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Academic Journal

In Silico Conformational Features of Botulinum Toxins A1 and E1 According to Intraluminal Acidification

Subjects: Clostridium botulinum; botulinum toxin; molecular dynamics

  • Source: EISSN: 2072-6651 ; Toxins ; https://hal.science/hal-03782462 ; Toxins, 2022, 14 (9), pp.644. ⟨10.3390/toxins14090644⟩

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Academic Journal

The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3)

Subjects: [SDV.TOX]Life Sciences [q-bio]/Toxicology; [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry; Molecular Biology/Biochemistry [q-bio.BM]

  • Source: ISSN: 0026-895X ; Molecular Pharmacology ; https://hal.science/hal-03435104 ; Molecular Pharmacology, 2021, 100 (3), pp.283 - 294. ⟨10.1124/molpharm.121.000303⟩.

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Academic Journal

Hormone-sensitive lipase: sixty years later

Subjects: Hormone-sensitive lipase; lipids; lipodystrophy

  • Source: ISSN: 0163-7827 ; Progress in Lipid Research ; https://ut3-toulouseinp.hal.science/hal-04828485 ; Progress in Lipid Research, 2021, 82, pp.101084. ⟨10.1016/j.plipres.2020.101084⟩.

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Academic Journal

Late-onset camptocormia caused by a heterozygous in-frame CAPN3 deletion

Subjects: Bent‑spine; Calpain-3; Calpainopathy

  • Source: ISSN: 0960-8966 ; Neuromuscular Disorders ; https://univ-evry.hal.science/hal-03358253 ; Neuromuscular Disorders, 2021, 31 (5), pp.450-455. ⟨10.1016/j.nmd.2021.02.012⟩.

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Academic Journal

Interplay between Histone and DNA Methylation Seen through Comparative Methylomes in Rare Mendelian Disorders

Subjects: rare diseases; DNA methylation profiling; histone methylation

  • Source: ISSN: 1661-6596.

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Academic Journal

Golgi Alpha1,2-Mannosidase IA Promotes Efficient Endoplasmic Reticulum-Associated Degradation of NKCC2

Subjects: kidney; NKCC2; protein quality control

  • Source: ISSN: 2073-4409 ; Cells ; https://hal.sorbonne-universite.fr/hal-03526059 ; Cells, 2021, 11 (1), pp.101. ⟨10.3390/cells11010101⟩.

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Academic Journal

Kinetic Study of the Avocado Sunblotch Viroid Self-Cleavage Reaction Reveals Compensatory Effects between High-Pressure and High-Temperature: Implications for Origins of Life on Earth

Subjects: structure–activity relationship; RNA World; hydrostatic pressure

  • Source: ISSN: 2079-7737 ; Biology ; https://hal.sorbonne-universite.fr/hal-03351804 ; Biology, 2021, 10 (8), pp.720. ⟨10.3390/biology10080720⟩.

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Academic Journal

A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells

Subjects: adenylate cyclase; Bordetella pertussis; calmodulin

  • Source: ISSN: 2198-3844 ; Advanced Science ; https://pasteur.hal.science/pasteur-03211832 ; Advanced Science, 2021, pp.2003630. ⟨10.1002/advs.202003630⟩.

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Academic Journal

PAK3 mutations responsible for severe intellectual disability and callosal agenesis inhibit cell migration

Subjects: [SDV]Life Sciences [q-bio]

  • Source: ISSN: 0969-9961.

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  • 1-10 ل  43 نتائج ل ""Catalytic Domain""