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Academic Journal

USP8 prevents aberrant NF-κB and Nrf2 activation by counteracting ubiquitin signals from endosomes

Subjects: Endosomes/genetics; Kelch-Like ECH-Associated Protein 1/genetics; NF-E2-Related Factor 2/genetics

  • Source: Endo , A , Fukushima , T , Takahashi , C , Tsuchiya , H , Ohtake , F , Ono , S , Ly , T , Yoshida , Y , Tanaka , K , Saeki , Y & Komada , M 2024 , ' USP8 prevents aberrant NF-κB and Nrf2 activation

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Academic Journal

MALDI-TOF Mass Spectrometry for interrogating ubiquitin enzymes

Subjects: E2 conjugating enzyme; E3 ligase; HECT E3 ligase

  • Source: De Cesare , V 2023 , ' MALDI-TOF Mass Spectrometry for interrogating ubiquitin enzymes ' , Frontiers in Molecular Biosciences , vol. 10 , 1184934 .

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Academic Journal

Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases

Subjects: ADP-Ribosylation; Humans; NAD/metabolism

  • Source: Chatrin , C , Gabrielsen , M , Buetow , L , Nakasone , M A , Ahmed , S F , Sumpton , D , Sibbet , G J , Smith , B O & Huang , D T 2020 , ' Structural insights into ADP-ribosylation of

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Academic Journal

PINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage

  • Source: Lambourne , O A , Bell , S , Wilhelm , L P , Yarbrough , E B , Holly , G G , Russell , O M , Alghamdi , A M , Fdel , A M , Varricchio , C , Lane , E L , Ganley , I G , Jones , A T , Goldberg , M S &

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Academic Journal

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling

Subjects: ARIH1; ARIH2; NEDD8 E3 ligase

  • Source: Kelsall , I R , Kristariyanto , Y A , Knebel , A , Wood , N T , Kulathu , Y & Alpi , A F 2019 , ' Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne RBR E3

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Academic Journal

E1B-55K-Mediated Regulation of RNF4 SUMO-Targeted Ubiquitin Ligase Promotes Human Adenovirus Gene Expression

Subjects: human adenovirus; HAdV; RNF4

  • Source: Müncheberg , S , Hay , R T , Ip , W H , Meyer , T , Weiß , C , Brenke , J , Masser , S , Hadian , K , Dobner , T & Schreiner , S 2018 , ' E1B-55K-Mediated Regulation of RNF4 SUMO-Targeted

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Academic Journal

The MALDI TOF E2/E3 ligase assay as universal tool for drug discovery in the ubiquitin pathway

Subjects: Ubiquitin; E3 ligase; E2 enzyme

  • Source: De Cesare , V , Johnson , C , Barlow , V , Hastie , C , Knebel , A & Trost , M 2018 , ' The MALDI TOF E2/E3 ligase assay as universal tool for drug discovery in the

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Academic Journal

Polyubiquitin-Photoactivatable Crosslinking Reagents for Mapping Ubiquitin Interactome Identify Rpn1 as a Proteasome Ubiquitin-Associating Subunit

Subjects: Binding Sites; Cross-Linking Reagents/chemistry; Molecular Docking Simulation

  • Source: Chojnacki , M , Mansour , W , Hameed , D S , Singh , R K , El Oualid , F , Rosenzweig , R , Nakasone , M A , Yu , Z , Glaser , F , Kay , L E , Fushman , D , Ovaa , H & Glickman , M H 2017 , '

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Academic Journal

An atypical ubiquitin ligase at the heart of neural development and programmed axon degeneration

Subjects: chemical biology; E3 ligase; MYCBP2

  • Source: Virdee , S 2022 , ' An atypical ubiquitin ligase at the heart of neural development and programmed axon degeneration ' , Neural Regeneration Research , vol. 17 , no. 11

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Academic Journal

Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase

Subjects: CMG helicase; FAF1; FAF2

  • Source: Fujisawa , R , Polo Rivera , C & Labib , K 2022 , ' Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase ' , eLife , vol. 11 ,

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