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Academic Journal

Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms

Subjects: Cancer-related isoforms; Saccharin; Secondary sulphonamides

  • Source: D'Ascenzio , M , Guglielmi , P , Carradori , S , Secci , D , Florio , R , Mollica , A , Ceruso , M , Akdemir , A , Sobolev , A P & Supuran , C T 2017 , ' Open saccharin-based secondary

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Academic Journal

Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer

Subjects: Adenosine/analogs & derivatives; Animals; Antineoplastic Agents/pharmacology

  • Source: Frame , S , Saladino , C , MacKay , C , Atrash , B , Sheldrake , P , McDonald , E , Clarke , P A , Workman , P , Blake , D & Zheleva , D 2020 , ' Fadraciclib (CYC065), a novel CDK inhibitor, targets

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Academic Journal

Photoactivatable prodrugs of antimelanoma agent Vemurafenib

Subjects: Cell line; Tumor; Cell proliferation

  • Source: Horbert , R , Pinchuk , B , Davies , P , Alessi , D & Peifer , C 2015 , ' Photoactivatable prodrugs of antimelanoma agent Vemurafenib ' , ACS Chemical Biology , vol. 10 , no. 9 , pp. 2099-2107 .

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Academic Journal

Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase

Subjects: Animals; Humans; Plasmodium falciparum/genetics

  • Source: Xie , S C , Wang , Y , Morton , C J , Metcalfe , R D , Dogovski , C , Pasaje , C F A , Dunn , E , Luth , M R , Kumpornsin , K , Istvan , E S , Park , J S , Fairhurst , K J , Ketprasit , N , Yeo , T ,

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Academic Journal

Phenyl Bis-Sulfonamide Keap1-Nrf2 Protein-Protein Interaction Inhibitors with an Alternative Binding Mode

Subjects: Assays; High-performance liquid chromatography; Inhibitors

  • Source: Georgakopoulos , N , Talapatra , S , Dikovskaya , D , Dayalan Naidu , S , Higgins , M , Gatliff , J , Ayhan , A , Nikoloudaki , R , Schaap , M , Valko , K , Javid , F , Dinkova-Kostova , A T ,

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Academic Journal

Antibiotics and antibiotic resistance genes in global lakes:A review and meta-analysis

Subjects: Antibiotic resistance genes; Antibiotics; Aquatic biota

  • Source: Yang , Y , Song , W , Lin , H , Wang , W , Du , L & Xing , W 2018 , ' Antibiotics and antibiotic resistance genes in global lakes : A review and meta-analysis ' , Environment International , vol. 116

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