نتائج البحث

Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia

• Authors : Wang, Xue Qing David; Fan, Dandan; Han, Qinyu

Subjects: Oncology

• Source: Cancer Discovery, 13(3), 724-745, (2023-03)

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ABT-869, a multitargeted receptor tyrosine kinase inhibitor: inhibition of FLT3 phosphorylation and signaling in acute myeloid leukemia

• Authors : Shankar, Deepa B.; Li, Junling; Tapang, Paul

• Source: Blood, 109(8), 3400-3408, (2007-04-15)

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E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice

• Authors : Kamps, Mark P.; Baltimore, David

• Source: Molecular and Cellular Biology, 13(1), 351-357, (1993-01)

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miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice

• Authors : Boldin, Mark P.; Taganov, Konstantin D.; Rao, Dinesh S.

Subjects: AML; acute myeloid leukemia; BMDM

• Source: Journal of Experimental Medicine, 208(6), 1189-1201, (2011-06-06)

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Myeloid Cell-Targeted miR-146a Mimic Inhibits NF-kB-Driven Inflammation and Leukemia Progression in Vivo

• Authors : Su, Yu-Lin; Wang, Xiuli; Mann, Mati

Subjects: cd19 antigens; inflammation; leukemia

• Source: Blood, 135(3), 167-180, (2020-01-16)

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Dual mechanisms by which MiR-125b represses IRF4 to induce myeloid and B cell leukemias

• Authors : So, Alex Yick-Lun; Sookram, Reeshelle; Chaudhuri, Aadel A.

Subjects: MiR-125b induces tumorigenesis in myeloid cells by repressing the expression of IRF4 at the mRNA and protein level. MiR-125b promotes oncogenesis in B cells that involves selection of cells that acquire genetic deletion of the gene encoding IRF4.

• Source: Blood, 124(9), 1502-1512, (2014-08-28)

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CREB is a critical regulator of normal hematopoiesis and leukemogenesis

• Authors : Cheng, Jerry C.; Kinjo, Kentaro; Judelson, Dejah R.

• Source: Blood, 111(3), 1182-1192, (2008-02-01)

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Myeloid cell-targeted miR-146a mimic alleviates NF-κB-driven cytokine storm without interfering with CD19-specific CAR T cell activity against B cell lymphoma

• Authors : Kortylewski, Marcin; Su, Yu-Lin; Wang, Xiuli

• Source: Journal for ImmunoTherapy of Cancer, 7(S1), Art. No. O61, (2019-11-06) ; 34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019), National Harbor, MD, 6-10

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Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A

• Authors : Chaudhuri, Aadel A.; So, Alex Yick-Lun; Mehta, Arnav

• Source: Proceedings of the National Academy of Sciences of the United States of America, 109(11), 4233-4238, (2012-03-13)

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MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

• Authors : O'Connell, Ryan M.; Chaudhuri, Aadel A.; Rao, Dinesh S.

Subjects: cancer; inflammation; myeloid

• Source: Proceedings of the National Academy of Sciences of the United States of America, 107(32), 14235-14240, (2010-08-10)

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