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Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

• Authors : Heazlewood, Chad; Cook, Matthew; Rajaraman, Eri

Subjects: Keywords: ethylnitrosourea; gamma interferon; interleukin 13

• Source: PLoS Medicine ; http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0050054

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A role for Alstrom syndrome protein, Alms1, in kidney ciliogenesis and cellular quiescence

• Authors : Li, Guochun; Vega, Raquel; Nelms, Keats

Subjects: Keywords: Alms1 protein; mouse; DNA binding protein

• Source: PLoS Genetics ; http://www.plosgenetics.org/article/fetchObjectAttachment.action?uri=info%3Adoi%2F10.1371%2Fjournal.pgen.0030008&representation=PDF ;

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Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity

• Authors : Liston, Adrian; Goodnow, Christopher

Subjects: Keywords: animal; article; autoimmunity

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Immunological Tolerance

• Authors : Ohashi, Pamela; Goodnow, Christopher; William E. Paul

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Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies

• Authors : Daley, Stephen R; Coakley, Kristen M; Hu, Daniel Y

Subjects: Rasgrp1; CD44; Helios+ T cells

• Source: eLife 2013;2:e01020

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Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids

• Authors : McNamara, Hayley; Cai, Yeping; Wagle, Mayura

• Source: Science Immunology ; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505664/

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Murine LRBA deficiency causes CTLA-4 deficiency in Tregs without progression to immunune dysregulation

• Authors : Burnett, Deborah L.; Parish, Ian; Masle-Farquhar, Etienne

• Source: Immunology and Cell Biology

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IL-2 prevents deletion of developing T-regulatory cells in the thymus

• Authors : Hu, Daniel; Wirasinha, Rushika; Goodnow, Christopher

• Source: Cell Death and Differentiation

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Dedicator of cytokinesis 8–deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells

• Authors : Tangye, Stuart; Pillay, Bethany; Randall, Katrina

Subjects: Dedicator of cytokinesis 8; CD41 T-cell differentiation; TH2 skewing

• Source: Journal of Allergy and Clinical Immunology

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A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation

• Authors : Oakes, Samantha R; Gallego-Ortega, David; Stanford, Prudence M

• Source: PLoS Genetics

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