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Academic Journal

Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut

Subjects: Microbial metabolism; Virology

  • Source: Becker , B , Wottawa , F , Bakr , M , Koncina , E , Mayr , L , Kugler , J , Yang , G , Windross , S J , Neises , L , Mishra , N , Harris , D , Tran , F , Welz , L , Schwärzler , J , Bánki , Z ,

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Academic Journal

α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity

Subjects: Parkinson’s disease; phosphorylation; α-synuclein

  • Source: Ghanem , S S , Majbour , N K , Vaikath , N N , Ardah , M T , Erskine , D , Jensen , N M , Fayyad , M , Sudhakaran , I P , Vasili , E , Melachroinou , K , Abdi , I Y , Poggiolini , I , Santos , P ,

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Academic Journal

Characterization of a novel cold-adapted intracellular serine protease from the extremophile Planococcus halocryophilus Or1

Subjects: calcium; characterization; cold adaptation

  • Source: Rasmussen , C B , Scavenius , C , Thøgersen , I B , Harwood , S L , Larsen , Ø , Bjerga , G E K , Stougaard , P , Enghild , J J & Thøgersen , M S 2023 , ' Characterization of a novel cold-adapted

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Academic Journal

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers

  • Source: Van Nyen , T , Planque , M , van Wagensveld , L , Duarte , J A G , Zaal , E A , Talebi , A , Rossi , M , Körner , P R , Rizzotto , L , Moens , S , De Wispelaere , W , Baiden-Amissah , R E M , Sonke ,

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Academic Journal

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

  • Source: Zachar , R , Thiel , S , Hansen , S , Henriksen , M L , Skjoedt , M O , Skjodt , K , Hamzaei , Z , Madsen , K , Lund , L , Hummler , E , Svenningsen , P & Jensen , B L 2022 , ' Mannan-binding lectin

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Academic Journal

FAM20C-Mediated Phosphorylation of MEPE and Its Acidic Serine- and Aspartate-Rich Motif

Subjects: ASARM; FAM20C; MEPE

  • Source: Christensen , B , Schytte , G N , Scavenius , C , Enghild , J J , McKee , M D & Sørensen , E S 2020 , ' FAM20C-Mediated Phosphorylation of MEPE and Its Acidic Serine-

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Academic Journal

Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion

  • Source: Keppner , A , Maric , D , Sergi , C , Ansermet , C , De Bellis , D , Kratschmar , D V , Canonica , J , Klusonova , P , Fenton , R A , Odermatt , A , Crambert , G , Hoogewijs , D & Hummler , E 2019 , '

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Academic Journal

The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation

Subjects: BETA-IG-H3; BIGH3; CORNEA

  • Source: Poulsen , E T , Nielsen , N S , Scavenius , C , Mogensen , E H , Risør , M W , Runager , K , Lukassen , M V , Rasmussen , C B , Christiansen , G , Richner , M , Vorum , H & Enghild , J J 2019 , ' The

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Academic Journal

Targeting of Liver Mannan-Binding Lectin-Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis

  • Source: Banda , N K , Desai , D , Scheinman , R I , Pihl , R , Sekine , H , Fujita , T , Sharma , V , Hansen , A G , Garred , P , Thiel , S , Borodovsky , A & Holers , V M 2018 , ' Targeting of Liver

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