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Academic Journal

IFNλ1 is a STING-dependent mediator of DNA damage and induces immune activation in lung cancer

Subjects: cancer immunology; CRISPR/Cas9; interferon lambda

  • Source: Godsk, S H, Jensen, C M S, Larsen, T V, Ahrenfeldt, J, Gammelgaard, K R & Jakobsen, M R 2024, 'IFNλ1 is a STING-dependent mediator of DNA

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Academic Journal

Comparing Photon and Charged Particle Therapy Using DNA Damage Biomarkers

Subjects: DNA damage; carbon-ion radiation therapy; proton therapy

  • Source: Ray, S, Cekanaviciute, E, Lima, I P, Sørensen, B S & Costes, S V 2019, 'Comparing Photon and Charged Particle Therapy Using DNA Damage

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Academic Journal

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

Subjects: DNA damage; IFI16; STING

  • Source: Dunphy, G, Flannery, S M, Almine, J F, Connolly, D J, Paulus, C, Jønsson, K L, Jakobsen, M R, Nevels, M M, Bowie, A G & Unterholzner, L 2018, 'Non-canonical Activation of the

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Academic Journal

High Resolution and Automatable Cytogenetic Biodosimetry Using In Situ Telomere and Centromere Hybridization for the Accurate Detection of DNA Damage:An Overview

Subjects: centromere; chromosomal instability; cytogenetic biodosimetry

  • Source: M’Kacher, R, Colicchio, B, Junker, S, El Maalouf, E, Heidingsfelder, L, Plesch, A, Dieterlen, A, Jeandidier, E, Carde, P & Voisin, P 2023, 'High Resolution and Automatable Cytogenetic Biodosimetry

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Academic Journal

NAD + supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

Subjects: Journal Article

  • Source: Hou, Y, Lautrup, S, Cordonnier, S, Wang, Y, Croteau, D L, Zavala, E, Zhang, Y, Moritoh, K, O'Connell, J F, Baptiste, B A, Stevnsner, T V, Mattson, M P & Bohr, V A 2018, 'NAD + supplementation

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Academic Journal

Surgically retrieved spermatozoa for ICSI cycles in non-azoospermic males with high sperm DNA fragmentation in semen

Subjects: assisted reproductive technology; ejaculated spermatozoa; in vitro fertilization

  • Source: Esteves, S C, Coimbra, I & Hallak, J 2023, 'Surgically retrieved spermatozoa for ICSI cycles in non-azoospermic males with high sperm DNA fragmentation in semen',

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Academic Journal

The p53 challenge of hematopoietic stem cell gene editing

Subjects: CRISPR-Cas; Cas9; DDR

  • Source: Dorset, S R & Bak, R O 2023, 'The p53 challenge of hematopoietic stem cell gene editing', Molecular Therapy Methods and Clinical Development, vol. 30, pp. 83-89.

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Academic Journal

Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns

Subjects: BRCA1 Protein/genetics; BRCA2 Protein/genetics; DNA Helicases/genetics

  • Source: Sørensen, S G, Shrikhande, A, Poulsgaard, G A, Christensen, M H, Bertl, J, Laursen, B E, Hoffmann, E R & Pedersen, J S 2023, 'Pan-cancer association of DNA repair

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Academic Journal

Erratum:Phosphorylation of MCT-1 by p44/42 MAPK is required for its stabilization in response to DNA damage (Oncogene (2007) 26 (2283-2289) DOI:10.1038/sj.onc.1210030)

  • Source: Nandi, S, Reinert, L S, Hachem, A, Mazan-Mamczarz, K, Hsu, H L, Hagner, P, He, H & Gartenhaus, R B 2007, 'Erratum : Phosphorylation of MCT-1 by p44/42 MAPK is required for its stabilization in

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Academic Journal

Extrachromosomal circular DNA in cancer: history, current knowledge, and methods

Subjects: DNA damage; copy number variation; double minutes

  • Source: Noer, J B, Hørsdal, O K, Xiang, X, Luo, Y & Regenberg, B 2022, 'Extrachromosomal circular DNA in cancer: history, current knowledge, and methods', Trends in Genetics,

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