Influence of body composition during hospitalization on lung function and inspiratory muscle strength in patients with COVID 19: cross-sectional study ; Influência da composição corporal durante a hospitalização sobre a função pulmonar e força da musculatura inspiratória em pacientes com COVID-19: estudo transversal

Introduction: Approximately 31% of hospitalized patients with COVID-19 lose more than 5% of their initial weight, leading to muscle weakness. Therefore, body composition has become the focus of investigation, to estimate pulmonary impairment, inspiratory muscle strength, and mortality. Objectives: To investigate whether weight loss and body composition of patients hospitalized with COVID-19 have any influence on lung function and inspiratory muscle strength after hospital discharge. Methods: Cross-sectional study. Adult patients were assessed after hospitalization due to COVID-19. Outcomes evaluated were lung function, maximal inspiratory pressure (MIP), body composition, and mortality. Correlations between the variables were estimated by Pearson's Correlation Coefficient. Results: Forced Vital Capacity (FVC) was correlated with weight loss, skeletal muscle mass, lean mass, left leg, and fat-free mass; Forced expiratory volume in the first second (FEV1) was correlated only with weight loss; and MIP was correlated with skeletal muscle mass, lean mass, left leg, right leg, and fat-free mass. Conclusion: A moderate correlation was observed between FVC and the analyzed body composition variables, except lean mass of left leg; between FEV1 and weight loss; and between MIP and the analyzed body composition variables, except weight loss. ; Introdução: Cerca de 31% dos pacientes hospitalizados com COVID-19 perdem mais de 5% de seu peso inicial, levando a fraqueza muscular. Portanto, a composição corporal tornou-se foco de investigação, para estimar comprometimento pulmonar, força da musculatura inspiratória e mortalidade. Objetivos: Investigar se a perda de peso e a composição corporal de pacientes internados com COVID-19 influenciam na função pulmonar e na força muscular inspiratória após alta hospitalar. Métodos: Estudo transversal. Pacientes adultos foram avaliados após internação por COVID-19. Os desfechos avaliados foram função pulmonar, pressão inspiratória máxima (Pimáx), composição corporal e mortalidade. As ...