Evidence Base Update of Psychosocial Treatments for Child and Adolescent Depression.

Publisher: Routledge Country of Publication: England NLM ID: 101133858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-4424 (Electronic) Linking ISSN: 15374416 NLM ISO Abbreviation: J Clin Child Adolesc Psychol Subsets: MEDLINE

Publication: 2008- : London : Routledge
Original Publication: Mahwah, N.J. : Lawrence Erlbaum Associates, c2002-

Evidence-Based Medicine*; Cognitive Behavioral Therapy/*statistics & numerical data ; Depression/*therapy ; Depressive Disorder/*therapy; Adaptation, Psychological ; Adolescent ; Child ; Depression/diagnosis ; Depressive Disorder/diagnosis ; Humans ; Male ; Psychotherapy ; Secondary Prevention

Depression in youth is prevalent and disabling and tends to presage a chronic and recurrent course of illness and impairment in adulthood. Clinical trial research in youth depression has a 30-year history, and evidence-based treatment reviews appeared in 1998 and 2008. The current review of 42 randomized controlled trials (RCTs) updates these reviews to include RCTs published between 2008 and 2014 (N = 14) and reevaluates previously reviewed literature. Given the growing maturity of the field, this review utilized a stringent set of methodological criteria for trial inclusion, most notable for excluding trials based in subclinical samples of youth that had been included in previous reviews (N = 12) and including well-designed RCTs with null and negative findings (N = 8). Findings from the current review suggest that evidence for child treatments is notably weaker than for adolescent interventions, with no child treatments achieving well-established status and the evidentiary basis of treatments downgraded from previous reports. Cognitive behavioral therapy (CBT) for clinically depressed children appears to be possibly efficacious, with mixed findings across trials. For depressed adolescents, both CBT and interpersonal psychotherapy are well-established interventions, with evidence of efficacy in multiple trials by independent investigative teams. This positive conclusion is tempered by the small size of the interpersonal psychotherapy literature (N = 6) and concern that CBT effects may be attenuated in clinically complicated samples and when compared against active control conditions. Data on predictors, moderators, and mediators are examined and priorities for future research discussed.

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R01 MH084935 United States MH NIMH NIH HHS; R01 MH100260 United States MH NIMH NIH HHS

Date Created: 20161122 Date Completed: 20170707 Latest Revision: 20181202

20231215

PMC5296370

10.1080/15374416.2016.1220310

27870579