- Patent Number:
12214,006
- Appl. No:
18/467250
- Application Filed:
September 14, 2023
- نبذة مختصرة :
Provided are a traditional Chinese medicine ointment for preventing and treating mastitis in dairy cows and a preparation method thereof, belonging to the technical field of veterinary traditional Chinese medicines. The traditional Chinese medicine ointment includes raw materials in parts by mass: 20-30 parts of dandelion, 20-30 parts of herba patriniae, 10-16 parts of Caulis Lonicerae Japonicae, 0.5-1 part of borneol, 0.03-0.05 part of polypeptide, 40-50 parts of auxiliary emulsifier, 40-50 parts of liquid paraffin and 100-130 parts of white vaseline. An amino acid sequence of the polypeptide is: Phe Phe Arg Lys Val Leu Lys Leu Ile Arg Lys Ile Trp Arg (SEQ ID NO. 1). In the application, dandelion, herba patriniae, Caulis Lonicerae Japonicae and borneol 1 are mixed, and polypeptide is added at the same time to prepare ointment.
- Inventors:
Hunan University of Science and Engineering (Hunan, CN)
- Assignees:
Hunan University of Science and Engineering (Hunan, CN)
- Claim:
1. A traditional Chinese medicine ointment for preventing and treating mastitis in dairy cows, comprising the following raw materials in parts by weight: 20-30 parts of dandelion, 20-30 parts of herba Patriniae, 10-16 parts of caulis Lonicerae japonicae, 0.5-1 part of borneol, 0.03-0.05 parts of polypeptide, 40-50 parts of auxiliary emulsifier, 40-50 parts of liquid paraffin, 0.5-1 parts of antioxidant, and 0.5-1 parts of preservative; wherein the amino acid sequence of the polypeptide is SEQ ID NO: 1.
- Claim:
2. The traditional Chinese medicine ointment for preventing and treating mastitis in dairy cows according to claim 1 , wherein the auxiliary emulsifier is glyceryl monostearate.
- Claim:
3. The traditional Chinese medicine ointment for preventing and treating mastitis in dairy cows according to claim 1 , wherein the antioxidant is alkyl gallate or butylated hydroxytoluene; and the preservative is ethylparaben.
- Patent References Cited:
2019/0336568 November 2019 Luo et al.
1660209 August 2005
1965976 May 2007
101342243 January 2009
102038748 May 2011
102716431 October 2012
102793780 November 2012
104983815 October 2015
105106215 December 2015
106496306 March 2017
107095940 August 2017
6359630 July 2018
2706689 November 2019
2021158517 August 2021
- Other References:
Gong et al. (The Herba Patriniae (Caprifoliaceae): A review on traditional uses, phytochemistry, pharmacology and quality control, J Ethnopharmacol, Aug. 23, 2020, 265: 113264,pp. 1-35). (Year: 2020). cited by examiner
Hao Jingfeng et al., “Comparison of in Vitro Bacteriostasis Effects of 20 Traditional Chinese Medicines on Three Pathogenic Bacteria of Subclinical Mastitis in Dairy Cow,” Chinese Journal of Veterinary Medicine, Feb. 2017, pp. 55-58. cited by applicant
Wang Yu et al., “Drug Sensitivity Test of Dandelion to Bacteria-caused Mastitis in Dairy Cows,” Breeding and feed, May 2015. cited by applicant
Ou Deyuan et al., “Study on the effect of compound traditional Chinese medicine ointment on clinical mastitis of dairy cows,” Guizhou Animal Husbandry and Veterinary, Aug. 2012. cited by applicant
Bai Dongdong et al., “Research progress on clinical effect and mechanism of traditional Chinese medicine in treating mastitis in dairy cows,” Progress in Veterinary Medicine, Oct. 2018, pp. 91-95, vol. 39, No. 10. cited by applicant
First Search Report for China Application No. 202211157538.4. cited by applicant
Supplemental Search Report for China Application No. 202211157538.4. cited by applicant
Office Action for China Application No. 202211157538.4, mailed Mar. 16, 2023. cited by applicant
Notice to Grant for China Application No. 202211157538.4, mailed May 2, 2023. cited by applicant
- Assistant Examiner:
Boeckelman, Jacob A
- Primary Examiner:
Kosar, Aaron J
- الرقم المعرف:
edspgr.12214006
Processing Request
No Comments.