Product derived from Rhodococcus ruber , and pharmaceutical use thereof

12102,654

17/421717

December 13, 2019

Isolated Rhodococcus ruber, a product derived from the Rhodococcus ruber (in particular, a product derived from the Rhodococcus ruber cell wall), a method for preparing the product derived from the Rhodococcus ruber, and use of the product derived from the Rhodococcus ruber in prevention and/or treatment of lichen planus. The product derived from the Rhodococcus ruber effectively reduce the erosion area of lichen planus and relieve pain.

LIAONING GREATEST BIO-PHARMACEUTICAL CO. LTD. (Benxi, CN)

Liaoning Greatest Bio-Pharmaceutical Co., Ltd. (Benxi, CN)

1. A method for preventing and/or treating erosive oral lichen planus in a subject in need thereof, comprising topically administering to the subject a therapeutically effective amount of Rhodococcus ruber cell wall skeleton.

2. The method of claim 1 , wherein the Rhodococcus ruber cell wall skeleton is derived from the isolated Rhodococcus ruber deposited with CGMCC with Accession No. 17431.

3. The method of claim 1 , wherein the therapeutically effective amount is in a unit dose of 1 μg to 1000 μg.

4. The method of claim 1 , wherein a therapeutically effective amount of Rhodococcus ruber cell wall skeleton is administered at a frequency selected from the group consisting of: 1 to 3 times per day, 1 to 6 times in two days, 1 to 9 times in three days, 1 to 14 times per week, and 1 to 60 times per month.

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1 547 607 June 2005
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