Apparatus, system and data carrier for automated peritoneal dialysis treatment

12064,542

17/271299

August 27, 2019

The present invention relates to an apparatus for performing an automated peritoneal dialysis treatment on a patient, the apparatus comprising: a first dialysis fluid port for receiving a first dialysis fluid having a first composition, which is determined by the concentrations of a set of first dialysis fluid constituents; a dialysis fluid line system connecting the first dialysis fluid port to a patient terminal; at least one dialysis fluid pump acting on the dialysis fluid line system and configured to convey the first dialysis fluid from the first dialysis fluid port to the patient terminal; and a control unit operably connected to the at least one pump; wherein the apparatus further comprises a second dialysis fluid port for receiving a second dialysis fluid having a second composition, which is determined by the concentrations of a set of second dialysis fluid constituents. The invention further relates to a system for automated peritoneal dialysis treatment and a data carrier comprising controlling software for such apparatus or system.

Fresenius Medical Care Deutschland GmbH (Bad Homburg, DE)

FRESENIUS CARE DEUTSCHLAND GMBH (Bad Homburg, DE)

1. An apparatus for performing an automated peritoneal dialysis treatment on a patient, the apparatus comprising: a first dialysis fluid port for receiving a first dialysis fluid having a first composition, which is determined by the concentrations of a set of first dialysis fluid constituents; a dialysis fluid line system connecting the first dialysis fluid port to a patient terminal; one dialysis fluid pump acting on the dialysis fluid line system and configured to convey the first dialysis fluid from the first dialysis fluid port to the patient terminal; and a control unit operably connected to the dialysis fluid pump; characterized in that the apparatus further comprises a second dialysis fluid port for receiving a second dialysis fluid having a second composition, which is determined by the concentrations of a set of second dialysis fluid constituents, wherein the second composition differs from the first composition in the concentration of at least one particular constituent, the first composition having a first concentration C1 of that particular constituent and the second composition having a second concentration C2 of that particular constituent; wherein also the second dialysis fluid port is connected to the patient terminal by the dialysis fluid line system and the dialysis fluid pump acting on the dialysis fluid line system and operably connected to the control unit is configured to convey the second dialysis fluid from the second dialysis fluid port to the patient terminal; and wherein the control unit is configured to control the dialysis fluid pump to apply a first volume V1 of the first dialysis fluid and a second volume V2 of a second dialysis fluid to the patient in the course of a multi-step inflow phase, wherein the first and second volumes V1 and V2 are determined based on a prescription that defines a target concentration C for the particular constituent, which lies in between the first and second concentrations C1 and C2 of the first and second dialysis fluids for the particular constituent, to obtain the target concentration C in the overall volume V applied to the patient during the multi-step inflow phase, wherein the dialysis fluid line system comprises a Y-junction where a first feed line connected to the first dialysis fluid port and a second feed line connected to the second dialysis fluid port combine into a common feed line connected to the patient terminal, wherein the apparatus comprises only one dialysis fluid pump acting on the common feed line and configured to convey both the first dialysis fluid and the second dialysis fluid from the respective dialysis fluid ports to the patient terminal.

2. The apparatus of claim 1 , wherein the apparatus comprises only the two dialysis fluid ports and wherein the overall volume V of dialysis fluid applied to the patient during the multi-step inflow phase corresponds to the sum V1+V2 of the first and second volume.

3. The apparatus of claim 1 , wherein at least two steps of the multi-step inflow phase are interrupted by an intermediate dwell phase to obtain an inflow-dwell-inflow profile.

4. The apparatus of claim 1 , wherein the particular constituent is an osmotic.

5. The apparatus of claim 1 , wherein the first and second compositions of the first and second dialysis fluids differ only in the concentration of the one particular constituent.

6. The apparatus of claim 1 , wherein the apparatus comprises a 3/2-way valve arranged at the Y-junction and operably connected to the control unit, wherein the valve enables inhibiting a flow of the second dialysis fluid from the second dialysis fluid port to the common feed line while enabling a flow of the first dialysis fluid from the first dialysis fluid port to the common feed line, and wherein the valve enables inhibiting a flow of the first dialysis fluid from the first dialysis fluid port to the common feed line while enabling a flow of the second dialysis fluid from the second dialysis fluid port to the common feed line.

7. The apparatus of claim 1 , wherein the particular constituent is glucose or a glucose derivative.

8. A system for performing an automated peritoneal dialysis treatment on a patient, the system comprising: an apparatus according to claim 1 ; and first and second dialysis fluid sources comprising the first and second dialysis fluids, said first and second dialysis fluid sources being connected to the first and second ports.

9. The system of claim 8 , wherein the first and second dialysis fluid sources are dialysis fluid receptacles.

10. The system of claim 8 , wherein the first and second dialysis fluid sources are dialysis fluid bags.

11. A data carrier comprising controlling software for an apparatus according to claim 1 .

12. The data carrier of claim 11 , wherein the controlling software is configured to apply a first volume V1 of the first dialysis fluid and a second volume V2 of a second dialysis fluid to the patient in the course of a multi-step inflow phase, wherein the first and second volumes V1 and V2 are determined based on a prescription that defines a target concentration C for the particular constituent, which lies in between the first and second concentrations C1 and C2 of the first and second dialysis fluids for the particular constituent, to obtain the target concentration C in the overall volume V applied to the patient during the multi-step inflow phase.

13. The data carrier of claim 11 , wherein the controlling software is configured to establish a prescription for automated peritoneal dialysis, in which a predetermined volume V and a predetermined concentration C for any dialysis fluid constituent within a range [C1, C2] may individually be selected for every cycle of the automated peritoneal dialysis treatment, wherein C1 corresponds to the concentration of said dialysis fluid constituent in one dialysis fluid reservoir and C2 corresponds to the concentration of said dialysis fluid constituent in another dialysis fluid reservoir.

14. The data carrier of claim 13 , wherein the controlling software is configured to establish the prescription on the basis of a user input comprising information on the intended equivalent volume and the intended equivalent concentration of the dialysis treatment.

15. A data carrier comprising controlling software for a system according to claim 8 .

3290069 August 2017
WO97/07837 March 1997

edspgr.12064542