Treatment of Fragile X Syndrome with cannabidiol

11458,110

16/986622

August 06, 2020

The present technology relates to a method of treating one or more behavioral symptoms of Fragile X Syndrome in a subject by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein one or more behavioral symptoms of Fragile X Syndrome are treated in the subject.

ZYNERBA PHARMACEUTICALS, INC. (Devon, PA, US)

ZYNERBA PHARMACEUTICALS, INC. (Devon, PA, US)

1. A method of treating a human suffering from Fragile X Syndrome comprising administering a therapeutically effective amount of isolated cannabidiol to the human suffering from Fragile X Syndrome to effectively treat the Fragile X Syndrome in the human in need thereof.

2. The method of claim 1 , wherein the therapeutically effective amount of isolated cannabidiol is between about 50 mg to 500 mg total daily.

3. The method of claim 2 , wherein the therapeutically effective amount of isolated cannabidiol is 250 mg total daily.

4. The method of claim 2 , wherein the therapeutically effective amount of isolated cannabidiol is 500 mg total daily.

5. The method of any of claim 3 and claim 4 , wherein the isolated cannabidiol is administered in two daily doses.

6. The method of claim 5 , wherein the isolated cannabidiol is (−)-cannabidiol.

7. The method of claim 1 , wherein the isolated cannabidiol is administered transdermally, and is formulated as a permeation-enhanced gel.

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