Compositions and methods for the sustained release of beta-alanine

9,636,315

14/626739

February 19, 2015

Methods and compositions are provided for increasing the anaerobic working capacity of muscle and other tissues. Also provided are compositions formulated for the sustained release of free beta-alanine. Also provided is a dietary supplement formulated, for example, as a solid food product, an edible suspension, liquid or semi-liquid as described herein.

Natural Alternatives International, Inc. (San Marcos, CA, US)

Natural Alternatives International, Inc. (San Marcos, CA, US)

1. A human dietary supplement comprising free beta-alanine or a salt of free beta-alanine, wherein the free beta-alanine or the salt of free beta-alanine in the human dietary supplement is a microencapsulated, sustained release formulation; wherein the human dietary supplement is a food product; wherein the human dietary supplement decreases the effects of paraesthesia, and delivers an effective amount of between about 0.1 g and about 10.0 g of the free beta-alanine or the salt of free beta-alanine to increase tissue anaerobic working capacity when provided over a prolonged period of time.

2. The human dietary supplement of claim 1 , wherein the food product is a solid food product.

3. The human dietary supplement of claim 2 , wherein the solid food product is selected from the group consisting of cookies, biscuits, chewing gum, lozenges, muffins, pies, tarts, cakes, and cereal flakes.

4. The human dietary supplement of claim 1 , wherein the food product is an edible suspension.

5. The human dietary supplement of claim 4 , wherein the edible suspension is selected from the group consisting of soup, yogurt, dairy or cheese spreads, margarines, meat and fish pastes, spreads and ice-cream.

6. The human dietary supplement of claim 1 , further comprising one or more additional components selected from the group consisting of vitamins, lipids, carbohydrates, amino acids, trace elements, colorings, flavors, artificial sweeteners, natural health improving substances, antioxidants, stabilizers, preservatives and buffers.

7. The human dietary supplement of claim 1 , further comprising creatine.

8. The human dietary supplement of claim 1 , further comprising one or more additional amino acids.

9. The human dietary supplement of claim 8 , wherein the one or more additional amino acids are selected from the group consisting of: L-cysteine and L-citrulline, and combinations thereof.

10. The human dietary supplement of claim 1 , further comprising one or more acetylcholine precursors selected from the group consisting of: choline chloride and phosphatidylcholine, and combinations thereof.

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