- Document Number:
20240198255
- Appl. No:
18/067711
- Application Filed:
December 18, 2022
- نبذة مختصرة :
A method comprising separating a plurality of arsenic species using a mixed mode column and a strong acid. The plurality of arsenic species includes at least one of each of an anionic arsenic species, a cationic arsenic species, a neutral arsenic species, and a zwitterionic arsenic species.
- Claim:
1. A method comprising: separating a plurality of arsenic species using a mixed mode column and a strong acid, the plurality of arsenic species including at least one of each of an anionic arsenic species, a cationic arsenic species, a neutral arsenic species, and a zwitterionic arsenic species.
- Claim:
2. The method of claim 1 wherein the anionic arsenic species is selected from the group consisting of arsenite, methylarsonate, dimethylarsinate, phenylarsonate, and arsenate.
- Claim:
3. The method of claim 1 wherein the neutral arsenic species includes trimethylarsinoxide.
- Claim:
4. The method of claim 1 wherein the zwitterionic arsenic species includes arsenobetaine.
- Claim:
5. The method of claim 1 wherein the cationic arsenic species is selected from the group consisting of arsenocholine and tetramethylarsonium.
- Claim:
6. The method of claim 1 wherein the mixed mode column includes a stationary phase with anionic and cationic functional groups.
- Claim:
7. The method of claim 1 wherein the strong acid has a pKa less than 2.0.
- Claim:
8. The method of claim 1 wherein the strong acid includes methanesulfonic acid, ethanesulfonic acid, hydrochloric acid, hydrobromic acid, iodic acid, chloric acid, or any combination thereof.
- Claim:
9. The method of claim 1 wherein separating the plurality of arsenic species further uses an organic solvent.
- Claim:
10. A method comprising: separating a plurality of arsenic species using a chromatography column and a strong acid having a counter ion, the counter ion including a weaker anion exchange species than NO3−.
- Claim:
11. The method of claim 10 wherein the plurality of arsenic species includes an anionic arsenic species selected from the group consisting of arsenite, methylarsonate, dimethylarsinate, phenylarsonate, and arsenate.
- Claim:
12. The method of claim 10 wherein the neutral arsenic species is selected from the group consisting of trimethylarsinoxide.
- Claim:
13. The method of claim 10 wherein the plurality of arsenic species includes a zwitterionic arsenic species.
- Claim:
14. The method of claim 13 wherein the zwitterionic arsenic species includes arsenobetaine.
- Claim:
15. The method of claim 10 wherein the plurality of arsenic species includes a cationic arsenic species selected from the group consisting of arsenocholine and tetramethylarsonium.
- Claim:
16. The method of claim 10 wherein chromatography column is a mixed mode column, and the mixed mode column includes a stationary phase with anionic and cationic functional groups.
- Claim:
17. The method of claim 10 wherein the strong acid has a pKa less than 2.
- Claim:
18. The method of claim 10 wherein the strong acid includes methanesulfonic acid, ethanesulfonic acid, hydrochloric acid, hydrobromic acid, iodic acid, chloric acid, or any combination thereof.
- Claim:
19. The method of claim 10 wherein separating the plurality of arsenic species further uses an organic solvent.
- Claim:
20. A method comprising: separating a plurality of arsenic species using a chromatography column and a strong acid, the plurality of arsenic species including at least two anionic arsenic species.
- Claim:
21. The method of claim 20 wherein the anionic arsenic species is selected from the group consisting of arsenite, methylarsonate, dimethylarsinate, phenylarsonate, and arsenate.
- Claim:
22. The method of claim 20 wherein the plurality of arsenic species further includes at least one zwitterionic arsenic species, at least one neutral arsenic species, or at least one cationic arsenic species.
- Claim:
23. The method of claim 22 wherein the neutral arsenic species includes dimethylarsinate.
- Claim:
24. The method of claim 22 wherein the zwitterionic arsenic includes arsenobetaine.
- Claim:
25. The method of claim 22 wherein the cationic arsenic species is selected from the group consisting of arsenocholine and tetramethylarsonium.
- Claim:
26. The method of claim 20 wherein the chromatography column is a mixed mode column and the mixed mode column includes a stationary phase with anionic and cationic functional groups.
- Claim:
27. The method of claim 20 wherein the strong acid has a counter ion that is a weaker anion exchange species than NO3−.
- Claim:
28. The method of claim 20 wherein the strong acid has a pKa less than 2.
- Claim:
29. The method of claim 20 wherein the strong acid includes methanesulfonic acid, ethanesulfonic acid, hydrochloric acid, hydrobromic acid, iodic acid, chloric acid, or any combination thereof.
- Claim:
30. The method of claim 20 wherein separating the plurality of arsenic species further uses an organic solvent.
- Current International Class:
01; 01
- الرقم المعرف:
edspap.20240198255
Processing Request
No Comments.