OXYGEN THERAPY ADMINISTRATION METHODS AND RELATED APPARATUS

20230372657

18/362059

July 31, 2023

Methods and apparatus for administering oxygen therapy, and particularly high-flow oxygen therapy is disclosed herein. A respiratory monitoring system may non-invasively determine greatest or average peak inspiratory flow rate of a patient based on biofeedback response received from the patient. Medical air, oxygen, or a combination of both may be delivered to the patient at a flow rate equal to greater than the determined greatest or average peak inspiratory flow rate of the patient to meet or exceed inspiratory demand of the patient. Fraction of oxygen inspired by the patient may be determined based on the greatest or average peak inspiratory flow rate and may be adjusted through high-flow oxygen therapy meeting inspiratory demand to prevent entrainment of ambient air or through low-flow oxygen therapy by accounting for entrainment of ambient air based on the greatest or average peak inspiratory flow rate to address medical needs of the patient.

1. A method of administering high-flow oxygen therapy, the method comprising the steps of: providing a respiratory monitoring system, the respiratory monitoring system comprising: a computer having: a frame; at least one display coupled to the frame; at least one processor coupled to the frame; and at least biofeedback sensor, the at least one biofeedback sensor configured to be attachable to a patient and electrically couplable to the computer, and receive biofeedback response from the patient; wherein the respiratory monitoring system being configured to measure tidal volume per breath, breaths per predetermined period of time, inspiratory time, expiratory time or combinations thereof based on the biofeedback response; providing an air-oxygen blender, the air-oxygen blender outputting air deliverable to the patient by a tube attachable to the patient and to the air-oxygen blender; attaching the at least one biofeedback sensor to the computer of the respiratory monitoring system and to the patient; determining a peak inspiratory demand based on the biofeedback response; and adjusting flow rate of air to be delivered to the patient from the air-oxygen blender to equal to or greater than the determined peak inspiratory demand.

2. The method of claim 1 wherein the respiratory monitoring system is further configured to determine a peak inspiratory flow rate and output the peak inspiratory flow rate via the at least one display of the respiratory monitoring system, and wherein the step of determining peak inspiratory demand comprises reading the peak inspiratory flow rate outputted by the at least one display of the respiratory monitoring system.

3. The method of claim 2 further comprising the steps of attaching the tube to the patient and to the air-oxygen blender and delivering the air to the patient.

4. The method of claim 3 wherein delivering the air to the patient comprises delivering the air to the patient at the adjusted flow rate until blood oxygen saturation of the patient reaches a desired percentage.

5. The method of claim 3 wherein delivering the air to the patient comprises delivering the air to the patient at an unadjusted flow rate, and then at the adjusted flow rate.

6. The method of claim 3 further comprising changing concentration of oxygen in the air delivered by the air-oxygen blender to achieve a desired fraction of oxygen inspired by the patient.

7. The method of claim 3 further comprising determining fraction of oxygen inspired by the patient based on the peak inspiratory flow rate, an unadjusted flow rate of the air being delivered to the patient, concentration of oxygen in the air being delivered to the patient, and flow rate of ambient air inspired by the patient.

8. The method of claim 3 further comprising determining fraction of oxygen inspired by the patient based on the adjusted flow rate of the air being delivered to the patient, and concentration of oxygen in the air being delivered to the patient.

9. The method of claim 8 further comprising decreasing the adjusted flow rate of air delivered to the patient from the air-oxygen blender as the fraction of oxygen inspired by the patient increases.

10. The method of claim 1 further comprising: adjusting concentration of oxygen of the breathing gas based on a desired fraction of oxygen to be inspired by the patient; and delivering the breathing gas to the patient at the adjusted flow rate and at the adjusted concentration of oxygen to achieve the desired fraction of oxygen to be inspired by the patient.

11. The method of claim 10 wherein the respiratory monitoring system is further configured to determine the fraction of oxygen inspired by the patient and output the fraction of oxygen inspired by the patient via the at least one display of the respiratory monitoring system, further comprising inputting the adjusted flow rate of the breathing gas being delivered to the patient into the respiratory monitoring system, and wherein the step of determining the fraction of oxygen inspired by the patient comprises reading the fraction of oxygen inspired by the patient outputted by the at least one display of the respiratory monitoring system.

12. The method of claim 10 wherein the oxygen concentration of the breathing gas is equal to or greater than 21%.

13. The method of claim 10 wherein the breathing gas is heated, humidified, and delivered to the patient through a nasal cannula.

14. The method of claim 10 further comprising decreasing the adjusted flow rate or the concentration of oxygen of the breathing gas delivered to the patient as the fraction of oxygen inspired by the patient increases.

15. A respiratory monitoring system used in administering oxygen therapy, comprising: a computer having: a frame; at least one display coupled to the frame; at least one processor coupled to the frame; at least one biofeedback sensor, the at least one biofeedback sensor configured to be attachable to a patient and electrically couplable to the computer, and receive biofeedback response from the patient; wherein the at least one processor is configured by program instructions to: determine tidal volume per breath, breaths per predetermined period of time, inspiratory time, expiratory time or combinations thereof; and determine a peak inspiratory demand in real time based on the biofeedback response; and wherein the at least one display is configured by program instructions to output the determined peak inspiratory demand in real time.

16. The respiratory monitoring system of claim 15 further comprising a sensor configured to detect flow rate of oxygen being delivered to the patient by an oxygen delivery system.

17. The respiratory monitoring system of claim 16 wherein the at least one processor is further configured by program instructions to determine fraction of oxygen inspired by the patient in real time.

18. The respiratory monitoring system of claim 17 wherein the at least one display is further configured to output the determined fraction of oxygen inspired by the patient in real time.

19. The respiratory monitoring system of claim 15 wherein the at least one processor is further configured by program instructions to determine fraction of oxygen inspired by the patient in real time based on the determined peak inspiratory demand.

20. The respiratory monitoring system of claim 15 wherein the at least one processor is further configured by program instructions to communicate with a microcontroller of an automated oxygen delivery system to adjust flow rate of oxygen being delivered to the patient to equal to or greater than the determined peak inspiratory demand to meet or exceed the patient's inspiratory demand.

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edspap.20230372657