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DRUG DETECTION USING COBALT THIOCYANATE AND EOSIN Y

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  • Publication Date:
    May 4, 2023
  • معلومة اضافية
    • Document Number:
      20230137342
    • Appl. No:
      17/910926
    • Application Filed:
      March 11, 2021
    • نبذة مختصرة :
      Materials and methods for testing unknown substances for the presence of an opioid are described.
    • Assignees:
      Bowling Green State University (Bowling Green, OH, US), Vuronyx Technologies LLC (Woburn, MA, US)
    • Claim:
      1. A testing assay comprising a substrate having a first area with Eosin Y thereon and a second area having cobalt thiocyanate thereon.
    • Claim:
      2. The testing assay of claim 1, wherein the substrate is a non-woven fabric.
    • Claim:
      3. The testing assay of claim 1, wherein substrate comprises polyester, polypropylene, nylon, cotton, cotton blends, wood pulp, polyurethane foam, or rayon fibers.
    • Claim:
      4. The testing assay of claim 1, wherein the substrate is paper.
    • Claim:
      5. The testing assay of claim 1, wherein the substrate comprises nitrocellulose or cardboard.
    • Claim:
      6. (canceled)
    • Claim:
      7. The testing assay of claim 1, wherein the testing assay is in the form of a wipe having the first area soaked in Eosin Y and the second area soaked in cobalt thiocyanate.
    • Claim:
      8. The testing assay of claim 1, wherein the first area has Eosin Y at a first pH thereon, and the substrate further comprises a third area having Eosin Y at a second pH thereon.
    • Claim:
      9. The testing assay of claim 8, wherein the first pH is 5 and the second pH is 7.
    • Claim:
      10. The testing assay of claim 1, wherein the first area comprises Eosin Y and phosphotungstic acid.
    • Claim:
      11. The testing assay of claim 1, wherein the first area comprises Eosin Y aggregates created with 0.02% w/w Eosin Y and 0.02% w/w phosphotungstic acid in a citrate or phosphate buffer.
    • Claim:
      12. The testing assay of claim 1, wherein the first area comprises Eosin Y aggregates created with from 0.005% w/w to 0.2% w/w Eosin Y and from 0.005% w/w to 0.5% w/w phosphotungstic acid in a citrate or phosphate buffer.
    • Claim:
      13. The testing assay of claim 1, wherein the first area comprises Eosin Y in water at a concentration of 0.02% w/w.
    • Claim:
      14. The testing assay of claim 1, wherein the first area comprises Eosin Y in water at a concentration ranging from 0.01% w/w to 0.1% w/w.
    • Claim:
      15. A wipe for testing for opioids, the wipe comprising a fabric substrate comprising Eosin Y in a first area.
    • Claim:
      16. The wipe of claim 15, wherein the Eosin Y comprises Eosin Y aggregates created with 0.02% w/w Eosin Y and 0.02% w/w phosphotungstic acid in a citrate or phosphate buffer.
    • Claim:
      17. The wipe of claim 15, wherein the wipe comprises Eosin Y in water at a concentration of 0.02% w/w.
    • Claim:
      18-23. (canceled)
    • Claim:
      24. A method for detecting the presence of an opioid, the method comprising contacting an unknown substance with the wipe of claim 15, wherein a color change in the first area from orange to pink indicates that the unknown substance is likely, or likely contains, an opioid.
    • Claim:
      25-28. (canceled)
    • Claim:
      29. A method for detecting the presence of an opioid, the method comprising contacting the testing array of claim 1 with an unknown substance and immersing the testing array in water, wherein a color change in the first area from orange to pink and a color change in the second area from orange to blue indicates that the unknown substance is likely, or likely contains, an opioid.
    • Claim:
      30-50. (canceled)
    • Claim:
      51. A testing assay comprising Eosin Y on a substrate, wherein: the testing assay is in the form of a test strip that is configured to change colors upon immersion in water following contact with an opioid, or the substrate is in the form of a fabric substrate comprising Eosin Y aggregates formed from Eosin Y and phosphotungstenic acid in a citrate or phosphate buffer.
    • Claim:
      52. (canceled)
    • Claim:
      53. The testing assay of claim 51, wherein the Eosin Y aggregates are formed from 0.02% w/w Eosin Y and 0.02% phosphotungstic acid in a citrate or phosphate buffer.
    • Claim:
      54-56. (canceled)
    • Current International Class:
      01
    • الرقم المعرف:
      edspap.20230137342