Noninvasive measurement of chemical substances

20070142718

11/601686

November 20, 2006

Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and/or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.

Abreu, Marcio Marc (North Haven, CT, US)

1-58. (canceled)

59. An ophthalmic system comprising: a tonometer for measuring intraocular pressure; a pachymetry apparatus for measuring corneal thickness; an electrical device altering the measured intraocular pressure based upon the measured corneal thickness to produce a corrected intraocular pressure; and a display identifying the corrected intraocular pressure.

60. The ophthalmic system according to claim 59, further comprising at least one of a keratometer for measuring corneal curvature, a biometer for measuring size of the eye and a device for measuring ocular rigidity.

61. The ophthalmic system according to claim 59, wherein the electrical device is a processor.

62. The ophthalmic system according to claim 59, further comprising a memory device.

63. An ophthalmic system comprising: a tonometer for measuring intraocular pressure; at least one of a keratometer for measuring corneal curvature, a biometer for measuring size of the eye and a device for measuring ocular rigidity; an electrical device altering the measured intraocular pressure based upon the at least one of the measured cornered curvature, the measured size of the eye and the measured ocular rigidity to produce a corrected intraocular pressure; and a display identifying the corrected intraocular pressure.

64. The ophthalmic system according to claim 63, further comprising a memory device.

65. The ophthalmic system according to claim 63, wherein the electrical device is a processor.

66. An ophthalmic system for determining an intraocular pressure correction signal or value comprising: a pachymetry apparatus for measuring corneal thickness; and an electrical device for calculating an intraocular pressure correction signal or value based on a deviation of said measured corneal thickness from a normal corneal thickness.

67. The ophthalmic system according to claim 66, further comprising a device for measuring intraocular pressure, the intraocular pressure correction signal or value is applied to the measured intraocular pressure to produce a corrected intraocular pressure.

68. The ophthalmic system according to claim 67, wherein the electrical device is a processor applying the intraocular pressure correction signal or value to the measured intraocular pressure.

69. The ophthalmic system according to claim 68, further comprising at least one of a memory device and a recording device.

70. The ophthalmic system according to claim 66, further comprising at least one of a keratometer for measuring corneal curvature, a biometer for measuring size of the eye and a device for measuring ocular rigidity.

71. The ophthalmic system according to claim 68, wherein the processor has access to lookup tables.

72. The ophthalmic system according to claim 66, further comprising a display identifying the intraocular correction signal.

73. An ophthalmic system for determining a corrected intraocular pressure value, said ophthalmic system comprising: a device for measuring an intraocular pressure; a pachymetry apparatus for measuring corneal thickness; an electrical device for adjusting said intraocular pressure value based on said corneal thickness to generate said corrected intraocular pressure value; and a display identifying the corrected intraocular pressure.

74. The ophthalmic system according to claim 73, wherein the electrical device is a processor.

75. The ophthalmic system according to claim 74, further comprising at least one of a memory device and a recording device.

76. The ophthalmic system according to claim 73, further comprising at least one of a keratometer for measuring corneal curvature, a biometer for measuring size of the eye and a device for measuring ocular rigidity.

77. The ophthalmic system according to claim 74, wherein the processor has access to lookup tables.

78. A method for determining an intraocular pressure correction value, said method comprising the steps of measuring corneal thickness value with a pachymetry apparatus; determining an intraocular pressure correction value using an electrical circuit based on a deviation of said measured corneal thickness value from normal corneal thickness; and reporting said intraocular pressure correction value.

79. The method according to claim 78, further including the step of determining deviation from normal corneal thickness once the corneal thickness is measured by said pachymetry apparatus.

80. The method according to claim 78, further including the step of measuring at least one of corneal curvature, size of the eye and ocular rigidity.

81. The method according to claim 78, wherein said determining step further comprises using a processor.

82. The method according to claim 81, wherein the processor accesses lookup tables.

83. A method for determining a corrected intraocular pressure value, said method comprising the steps of measuring an intraocular pressure value; measuring a corneal thickness value; adjusting said intraocular pressure value based on said corneal thickness value using an electrical circuit to generate said corrected intraocular pressure value; and reporting said intraocular pressure correction value.

84. The method according to claim 83, further including the step of determining deviation from normal corneal thickness of said measured corneal thickness.

85. The method according to claim 83, wherein said determining step further comprises using a processor.

86. The method according to claim 83, further including the step of measuring at least one of corneal curvature, size of the eye and ocular rigidity.

87. The method according to claim 83, wherein the processor accesses lookup tables.

88. A method for determining an intraocular pressure correction value, said method comprising the steps of measuring at least one of corneal thickness, corneal curvature, size of the eye and ocular rigidity; determining an intraocular pressure correction value using an electrical circuit based on a deviation of said at least one of corneal thickness, corneal curvature, size of the eye and ocular rigidity from a normal value; and reporting said intraocular pressure correction value.

89. A method for determining corrected intraocular pressure, said method comprising the steps of measuring an intraocular pressure value; measuring at least one of corneal thickness, corneal curvature, size of the eye and ocular rigidity; adjusting said intraocular pressure value based on said at least one of corneal thickness, corneal curvature, size of the eye and ocular rigidity; using an electrical circuit to generate said corrected intraocular pressure value; and reporting said intraocular pressure correction value.

600323/000

61; 61

edspap.20070142718