نبذة مختصرة : Aiben Kayierhan,1,2,* Abuduwupuer Haibier,1,2,* Aikebaierjiang Aisaiti,1,2,* Alimujiang Aximu,1,2 Liang Ma,1,2 Yuntao Liu,1,2 Tuerhongjiang Abudurexiti1,2 1Minimally Invasive Spine Surgery, Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, Peopleâs Republic of China; 2Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, Peopleâs Republic of China*These authors contributed equally to this workCorrespondence: Tuerhongjiang Abudurexiti, Email 2676661815@qq.comObjective: To evaluate the clinical effectiveness of endoscopic removal of spinal infections and posterior pedicle surgery, including bone grafting, fixation, and chemotherapy, and to outline preventive strategies for complications, offering guidance for clinical practice.Methods: 128 spinal infectious disease patients (2018â 2022) were categorized into Group A (endoscopic removal, n=44) and Group B (posterior pedicle removal+bone grafting+fixation, n=84). Pre-surgery, all received quadruple antibiotic therapy. Metrics tracked: operation time, blood loss, drainage, recovery, stay, transfusion, complications, and pre/post-surgery VAS, ODI, ESR, CRP, PCT, D-dimer, NLR, Hb, albumin.Results: (1) Preoperative data: There were no statistically significant differences in age, gender, body mass index, involved segments, past medical history (cardiovascular and cerebrovascular diseases, respiratory diseases, endocrine system diseases, metabolic diseases and tuberculosis), smoking history, preoperative erythrocyte sedimentation rate, C-reactive protein, procalcitonin, D-dimer, lymphocyte and neutrophil-lymphocyte ratio, hemoglobin, total protein, waist VAS score and waist ODI score (P> 0.05). (2) The main postoperative indexes were significantly lower than those of group B at the last follow-up at 3 months and the last follow-up in group A, and the difference was significant (P< 0.05), the hemoglobin and total pro
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