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Dermal absorption of high molecular weight parent and alkylated polycyclic aromatic hydrocarbons from manufactured gas plant soils using in vitro assessment

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  • معلومة اضافية
    • Publisher Information:
      Elsevier 2024-05-05
    • نبذة مختصرة :
      An enhanced in vitro human dermal bioavailability method was developed to measure the release of twenty parent and seven alkylated high molecular weight (HMW) polycyclic aromatic hydrocarbons (PAHs) from contaminated soils collected from five former manufactured Gas Plants (MGP) in England. GC-MS/MS was used to quantify HMW PAHs in soil, Strat-M artificial membrane representing skin, and synthetic receptor solution (RS) representing systemic circulation at 1-h, 10-h, and 24-h timesteps. Fluoranthene and pyrene exhibited the highest fluxes from soils to membrane (ranging from 9.5 - 281 ng/cm2/h) and soil to RS (
    • الموضوع:
      Publication - Article; PeerReviewed
    • Note:
      text
      English
    • Other Numbers:
      UKNRA oai:nora.nerc.ac.uk:537137
      Williams-Clayson, Alison M.; Vane, Christopher H. ORCID: https://orcid.org/0000-0002-8150-3640 ; Jones, Matthew D.; Thomas, Russell; Taylor, Christopher; Beriro, Darren J.. 2024 Dermal absorption of high molecular weight parent and alkylated polycyclic aromatic hydrocarbons from manufactured gas plant soils using in vitro assessment. Journal of Hazardous Materials, 469, 133858. https://doi.org/10.1016/j.jhazmat.2024.133858
      1427403618
    • Contributing Source:
      NERC OPEN RES ARCH
      From OAIster®, provided by the OCLC Cooperative.
    • الرقم المعرف:
      edsoai.on1427403618
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